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NCT03509324 Clinical Trial

Effectiveness of Glucose Control, β Cell Function in Response to Short-term Insulin Pump Therapy in Type 2 Diabetes

Diabetes Mellitus, Type 2 Clinical Trial

Official title:
Effectiveness and Determinants of Glucose Control, β-cell Function in Response to Short-term Intensive Insulin Pump Therapy in Different Duration of Type 2 Diabetes Mellitus.

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03509324
Other study ID # DMT20150410
Secondary ID
Status Completed
Phase Phase 4
First received April 17, 2018
Last updated April 17, 2018
Start date March 1, 2015
Est. completion date June 30, 2015

Study information
Verified date April 2018
Source Sun Yat-sen University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The purpose of this study is to investigate and evaluate the significance of intravenous glucose tolerance test in assessment of β-cell function improvement after short course of intensive insulin therapy, trying to illustrate the relationship between fasting plasma glucose and acute insulin release under different stage of type 2 diabetes with poor glycemic control.

Recruitment information / eligibility
Status Completed
Enrollment 67
Est. completion date June 30, 2015
Est. primary completion date June 30, 2015
Accepts healthy volunteers No
Gender All
Age group 20 Years to 75 Years
Eligibility Inclusion Criteria: different course of type 2 diabetes with poor glycemic control

Exclusion Criteria:

- acute complication or severe comorbidities

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Insulin LISPRO
receive short-term insulin pump therapy by using insulin LISPRO, continue treatment for 7 more days when euglycemia achieved

Locations
Country Name City State
China endocrinology department of the first affiliated hospital of Sun Yat-sen University Guangzhou Guangdong

Sponsors (1)
Lead Sponsor Collaborator
Sun Yat-sen University

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary fasting plasma glucose after insulin therapy 10 hour
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