Clinical Trial Details
— Status: Terminated
Administrative data
| NCT number |
NCT02660476 |
| Other study ID # |
JIRB: 14-0032. MRC: #14461/14 |
| Secondary ID |
|
| Status |
Terminated |
| Phase |
|
| First received |
|
| Last updated |
|
| Start date |
October 2014 |
| Est. completion date |
June 1, 2023 |
Study information
| Verified date |
June 2023 |
| Source |
Weill Cornell Medical College in Qatar |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Observational
|
Clinical Trial Summary
QUDOS is a cross-sectional population study aiming to answer key questions about diabetes and
its complications in Qatar as well as identify factors associated with the development and
progression of diabetes complications.
Description:
QUDOS aims to gain a better understanding of diabetes in primary and secondary care over a
period of 24 months.
A range of patients with diabetes will be sampled (including those with Type 1 diabetes as
this group is under-studied in Qatar). This will be important in designing appropriate
intervention plans that will improve diabetic patients' health conditions to prevent or delay
the onset of complications and will provide a strong foundation for longitudinal study.
The broad objectives of the study are:
QUDOS 1: Aims to recruit 1,700 diabetic patients (including 200 with type 1 diabetes mellitus
(independent of healthcare setting)) attending the hospitals and primary care and to collect
the following data:
- Demographics: age, sex, ethnicity, socio-economic background, smoking status;
- Anthropometrics: vital signs, height, weight, body fat percentage, fat mass, neck and
waist circumference;
- Medical History: medications, complications, comorbidities, latest HbA1c and lipid
profiles and family medical history;
- Routine laboratory data;
- Lifestyle: diet, physical activity,;
- Sleep: quality and daytime sleepiness;
- Cognition and Mental Health: depression, anxiety, stress and memory;
- Diabetes microvascular complications: diabetic neuropathy, urine albumin/creatinine
ratio; routine retinal screening data.
- Gut microbiome from a stool sample
QUDOS 2: To further characterise 500 patients, from the total 1500 patients with T2DM
recruited in QUDOS 1, who accept to continue with QUDOS 2 (a more detailed study and
assessment).
This phase aims to concentrate on the following aspects:
- Obstructive sleep apnoea;
- Sleep duration and quality;
- Diet;
- Objective physical activity;
- Stress;
- Quality of Life;
- Depression and anxiety;
- Perceived control of health;
- Detailed neuropathy screening;
- Cardiovascular function;
- Cognitive function;
- Biological samples.
