Use of Copeptin in Diabetes Insipidus

Status Completed

Clinical Trial Summary

Prospective evaluation of the novel biomarker copeptin in the differential diagnosis of diabetes insipidus against the standard diagnostic test methods.

Clinical Trial Description

Purpose of this study is to compare the overall diagnostic accuracy of the three following diagnostic test procedures in diabetes insipidus (central, nephrogenic) and primary polydipsia: a) classical water deprivation test alone, b) classical water deprivation test plus plasma copeptin cut-off levels, c) hypertonic saline infusion test plus plasma copeptin measurement.

The investigators hypothesize that firstly b) and c) is better as a). Secondly the investigators hypothesize that c) is non-inferior to b). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01940614
Study type	Observational
Source	University Hospital, Basel, Switzerland
Contact
Status	Completed
Phase
Start date	July 2013
Completion date	December 2017

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03572166` - Use of Copeptin Measurement After Arginine Infusion for the Differential Diagnosis of Diabetes Insipidus - the CARGOx Study	N/A
Completed	`NCT04550520` - Copeptin After a Subcutaneous Stimulation With Glucagon in Adults	N/A
Terminated	`NCT02460354` - Metformin and Congenital Nephrogenic Diabetes Insipidus	Phase 1
Completed	`NCT02523001` - Effect of Statin Treatment on Urinary AQP2 (uAQP2/01)	N/A
Active, not recruiting	`NCT04351945` - Endocrine Changes and Their Correction in Heart and Lung Transplant Recipients and Donors
Completed	`NCT00757276` - Copeptin in the Diagnosis and Differential Diagnosis of Diabetes Insipidus. The CoSIP-Study	N/A
Recruiting	`NCT02841553` - Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study
Completed	`NCT04648137` - Circulating Oxytocin Changes in Response to the Oxytocin System Stimulator MDMA in Patients With Diabetes Insipidus and Healthy Controls	N/A
Active, not recruiting	`NCT00004364` - Study of Novel Types of Familial Diabetes Insipidus	N/A
Completed	`NCT00004363` - Study of the Pathogenesis and Pathophysiology of Familial Neurohypophyseal Diabetes Insipidus	N/A
Completed	`NCT02132676` - Shared Health Appointments and Reciprocal Enhanced Support
Completed	`NCT02455414` - Tracking Neurodegeneration in Early Wolfram Syndrome