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NCT00698698 Clinical Trial

Study on Tear Proteins in Diabetic Retinopathy of Type 2 Diabetics

Diabetes Mellitus Clinical Trial

Official title:
Tear Proteins and Diabetic Retinopathy

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT00698698
Other study ID # Tear proteins
Secondary ID
Status Active, not recruiting
Phase N/A
First received June 13, 2008
Last updated January 30, 2009
Start date January 2009
Est. completion date June 2011

Study information
Verified date January 2009
Source Dow University of Health Sciences
Contact n/a
Is FDA regulated No
Health authority Pakistan: Ministry of Health
Study type Observational

Clinical Trial Summary

Diabetes mellitus is becoming a global epidemic. There is a need to devise a non invasive method for detection of diabetes and its related complication. Tear proteins are easy to collect causing no harm to a patient and different studies indicate that tear proteins of diabetic patients are significantly different from non diabetic population. This difference in the composition of tear proteins become more pronounced with advancement of diabetic retinopathy.

Description:

Diabetes mellitus causes a significant alteration in tear proteins. If we analyze tear proteins by means of electrophoresis, HPLC, and mass spectroscopy.

We can find different type of tear proteins in different grades of diabetic retinopathy these biomarkers can help in mass screening , diagnosis and management of diabetic population.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 350
Est. completion date June 2011
Est. primary completion date December 2010
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 30 Years to 90 Years
Eligibility Inclusion Criteria:

- diabetic patients with type 2 diabetes

- age above 30

- willing to participate

Exclusion Criteria:

- ocular surface disorders.

- collagen vascular diseases

- Limbal hyperemia

- previous ocular surgery

- creatinine level above 1.0

- liver diseases

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Locations
Country Name City State
Pakistan Dow University of Health Sciences Karachi Sindh

Sponsors (1)
Lead Sponsor Collaborator
Dow University of Health Sciences

Country where clinical trial is conducted

Pakistan, 

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