Diabetes Clinical Trial
Official title:
ORWH:SCOR on Sex and Gender Factors Affecting Women's Incontinence
This study consists of two studies with overlapping cohorts. One is a follow up
epidemiological study of urinary incontinence, the other is a case control study of lower
urinary tract dysfunction in women with diabetes.
Study One:
Subjects for the study will be a retrospective cohort of 2100 middle-aged and older women
from a large health maintenance organization who have participated in the Reproductive Risk
Factor for Incontinence Study at Kaiser (RRISK). The RRISK I study assembled a retrospective
cohort of long-term female Kaiser Permanente members to determine the association between
specific childbirth events, hysterectomy, hormone use and urinary incontinence later in
life. The study also provides descriptive information on urinary incontinence by type, age,
ethnicity, severity and age of onset.
Study Two:
Women with diabetes have a 30-70% increased risk of lower urinary tract dysfunction,
including lower urinary tract symptoms, urinary incontinence, and ultimately bladder
cystopathy. This sudy investigates the natural history, risk factors, and possible
mechanisms of lower urinary tract dysfunction and infection among women with type 2 diabetes
as compared to women without diabetes.
n/a
Observational Model: Case-Only, Time Perspective: Retrospective
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