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An Open-Label, FIH Study Evaluating the Safety and Tolerability of VCTX210A Combination Product in Subjects With T1D

Diabetes Mellitus Clinical Trial

Official title:
An Open-Label, First-In-Human Study Evaluating the Safety and Tolerability of VCTX210A Combination Product in Subjects With Type 1 Diabetes Mellitus (T1D)

Clinical Trial Summary

This is an open-label, multicenter, Phase 1 study evaluating the safety and tolerability of VCTX210A combination product in patients with T1D

Clinical Trial Description

VCTX210A combination product (unit) comprises 2 components: (1) allogeneic pancreatic endoderm cells (PEC210A) genetically modified using Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated protein 9 (CRISPR/Cas9) to promote immune evasiveness and survival, and (2) a durable, removable, perforated device designed to deliver and retain the PEC210A cells. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05210530
Study type Interventional
Source CRISPR Therapeutics
Contact
Status Completed
Phase Phase 1
Start date January 24, 2022
Completion date January 19, 2023
View Details
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