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Levels of Neuregulin-4 and Its Receptor ErbB4 in Periodontitis Patients With and Without Diabetes Type 2

Diabetes Mellitus Clinical Trial

Official title:
Gingival Crevicular Fluid and Salivary Levels of Neuregulin-4 and Its Receptor ErbB4 in Patients With Stage III and IV Periodontitis With and Without Type 2 Diabetes: An Observational Study

Clinical Trial Summary

The aim of this study is to assess the levels of neuregulin-4 and its receptor ErbB4 in the GCF and saliva in stage III and IV periodontitis patients with and without type 2 diabetes mellitus.

Clinical Trial Description

The aim of this study is to measure the levels of Nrg4 and ErbB4 in the GCF and saliva of periodontitis stage III and IV patients with and without type 2 diabetes mellitus and to correlate their levels with the periodontal clinical parameters and the blood glucose levels including the fasting plasma glucose level (FPG) and glycated hemoglobin (HbA1c). This study will be conducted in the Oral Medicine and Periodontology department, Faculty of Dentistry- Cairo University, Egypt. Patients will be selected from the outpatient clinic of the department of Oral Medicine and Periodontology, Faculty of Dentistry-Cairo University. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04930588
Study type Observational
Source Cairo University
Contact Asmaa Samir, Master
Phone 01000797021
Email Asmaaabdelfatah@dentistry.cu.edu.eg
Status Recruiting
Phase
Start date June 1, 2021
Completion date December 2023
View Details
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