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Integration of Continuous Glucose Monitoring Into a BiHormonal Closed-Loop Artificial Pancreas — CL2  

Diabetes Mellitus Clinical Trial

Official title:
Integration of Continuous Glucose Monitoring Into a Bi-Hormonal Closed-Loop Artificial Pancreas for Automated Management of Type 1 Diabetes

Clinical Trial Summary

The investigators hypothesize that our closed-loop glucose-control system can provide BG control in subjects with type 1 diabetes using the estimated BG signal from a CGM as the input signal to the controller.

Clinical Trial Description

To test the safety and efficacy of our control system in the bi-hormonal configuration in regulating BG in adults (18 years of age or older) and in children (12-17 years of age) with type 1 diabetes based on interstitial-fluid (ISF) glucose data from a CGM. Experiments will be 51 hours in length incorporating 6 meals and two (night) sleep periods. In order to evaluate the effect of exercise on BG control, the last 48 hours of the experiment will be divided into two 24 hour blocks, the second of which will contain a period of structured exercise near the beginning of the block. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01161862
Study type Interventional
Source Boston University Charles River Campus
Contact
Status Completed
Phase N/A
Start date July 2010
Completion date June 2013
View Details
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