Diabetes Mellitus, Type 2 Clinical Trial
Official title:
Reversibility of Brain Glucose Transport and Metabolism in T2DM
The goal of this clinical trial is to learn about the effects of high blood glucose levels in the brain and assess if the changes seen in individuals with poorly control T2DM can be reversed with good glucose control. The main question[s] it aims to answer are: - To determine, whether abnormalities in brain glucose transport seen in individuals with uncontrolled diabetes, can be improved with better glucose control. - Assess which factors, (duration of diabetes mellitus (DM) and glycemic control) contribute to changes in glucose transport Participants will have: - A screening visit - placement of a continuous glucose monitor (CGM) 2 weeks before the first magnetic resonance spectroscopy (MRS) at week 0 - Additional visits/phone calls for intensification of diabetes management and nutrition visits - Second magnetic resonance spectroscopy (MRS) at week 12
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