Diabetes Mellitus, Type 2 Clinical Trial
Official title:
Glucagon-like Peptide-1 (GLP-1) Agonists: Treatment Utilization Patterns and Risk of Acute Pancreatitis
This study will assess the utilization patterns (adherence, source of the index antidiabetic
agent (ADA) and treatment modification) of the marketed glucagon-like peptide-1 (GLP-1)
receptor agonists (exenatide and liraglutide), dipeptidyl-peptidase-4 (DPP-4) inhibitors
(sitagliptin, saxagliptin, and linagliptin) and other ADAs and the incidence rate of acute
pancreatitis among the users of these GLP-1 receptor agonists and users of DPP-4 inhibitors,
separately, in comparison to other ADAs.
The proposed study will help in understanding the treatment utilization patterns and the
incidence rate of acute pancreatitis among users of the marketed GLP-1 receptor agonists.
This study differs from previous observational studies by including both exenatide and
liraglutide and follow-up time is expected to be longer in the current study (2005 - 2011).
This study will be a retrospective cohort study conducted in the Truven (Thomson Reuters)
commercial health insurance database from 2005-2011.
n/a
Observational Model: Cohort, Time Perspective: Retrospective
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