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A Comparison of Strict Glucose Control With Usual Care at the Time of Islet Cell Transplantation

Diabetes Mellitus, Type 1 Clinical Trial

Official title:
A Comparison of Strict Glucose Control With Usual Care at the Time of Islet Cell Transplantation

Clinical Trial Summary

Islet transplants for those with type 1 diabetes have enabled many to initially eliminate insulin, however, only a fraction of the transplanted cells typically survive and the functioning of these decrease over time. As a result, most patients will eventually require some insulin. Currently, the cause of this poor survival and decrease in function is not understood; although previous research has demonstrated that even a slightly elevated level of blood glucose can impair islet function. This study will determine if strict blood glucose control at the time of islet transplantation, when the cells are the most fragile, will improve the survival and functioning of transplanted islet cells three months after transplantation.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01123122
Study type Interventional
Source Vancouver Coastal Health
Contact
Status Withdrawn
Phase N/A
Start date September 2011
Completion date September 2015
View Details
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