Clinical Trials Logo

Clinical Trial Summary

Prospective evaluation of the novel biomarker copeptin in the differential diagnosis of diabetes insipidus against the standard diagnostic test methods.


Clinical Trial Description

Purpose of this study is to compare the overall diagnostic accuracy of the three following diagnostic test procedures in diabetes insipidus (central, nephrogenic) and primary polydipsia: a) classical water deprivation test alone, b) classical water deprivation test plus plasma copeptin cut-off levels, c) hypertonic saline infusion test plus plasma copeptin measurement.

The investigators hypothesize that firstly b) and c) is better as a). Secondly the investigators hypothesize that c) is non-inferior to b). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01940614
Study type Observational
Source University Hospital, Basel, Switzerland
Contact
Status Completed
Phase
Start date July 2013
Completion date December 2017

See also
  Status Clinical Trial Phase
Completed NCT03572166 - Use of Copeptin Measurement After Arginine Infusion for the Differential Diagnosis of Diabetes Insipidus - the CARGOx Study N/A
Completed NCT04550520 - Copeptin After a Subcutaneous Stimulation With Glucagon in Adults N/A
Terminated NCT02460354 - Metformin and Congenital Nephrogenic Diabetes Insipidus Phase 1
Completed NCT02523001 - Effect of Statin Treatment on Urinary AQP2 (uAQP2/01) N/A
Active, not recruiting NCT04351945 - Endocrine Changes and Their Correction in Heart and Lung Transplant Recipients and Donors
Completed NCT00757276 - Copeptin in the Diagnosis and Differential Diagnosis of Diabetes Insipidus. The CoSIP-Study N/A
Recruiting NCT02841553 - Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study
Not yet recruiting NCT06368817 - A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma Phase 2
Completed NCT04648137 - Circulating Oxytocin Changes in Response to the Oxytocin System Stimulator MDMA in Patients With Diabetes Insipidus and Healthy Controls N/A
Active, not recruiting NCT00004364 - Study of Novel Types of Familial Diabetes Insipidus N/A
Completed NCT00004363 - Study of the Pathogenesis and Pathophysiology of Familial Neurohypophyseal Diabetes Insipidus N/A
Completed NCT02132676 - Shared Health Appointments and Reciprocal Enhanced Support
Completed NCT02455414 - Tracking Neurodegeneration in Early Wolfram Syndrome