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Dermatitis clinical trials

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NCT ID: NCT03260595 Completed - Healthy Clinical Trials

A Study of Crisaborole Ointment 2% in Adult Japanese Healthy Subjects and Adult Japanese Subjects With Mild To Moderate Atopic Dermatitis

Start date: September 13, 2017
Phase: Phase 1
Study type: Interventional

This is a Phase 1 parallel-cohort study of crisaborole ointment 2% to evaluate the skin irritation potential in adult Japanese healthy subjects in Cohort 1, and to evaluate the safety, tolerability and PK in adult Japanese subjects with mild to moderate AD in Cohort 2.

NCT ID: NCT03257644 Completed - Atopic Dermatitis Clinical Trials

A Pharmacokinetic Study of Ruxolitinib Phosphate Cream in Pediatric Subjects With Atopic Dermatitis

Start date: September 21, 2017
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety, tolerability and the pharmacokinetics (PK) of topical ruxolitinib cream applied to pediatric subjects (age ≥ 2 to 17 years) with atopic dermatitis (AD).

NCT ID: NCT03255980 Completed - Quality of Life Clinical Trials

Monocenter, Open Label Clinical Investigation on the Treatment of Radiation Induced Dermatitis With Xonrid®

Start date: June 15, 2017
Phase: N/A
Study type: Interventional

To evaluate the performance of Xonrid® in the prevention and treatment of G2 radiation dermatitis in breast and head & neck cancer patients.

NCT ID: NCT03253666 Completed - Melanoma Clinical Trials

Nurses' Health Study and Health Professionals Follow-Up Study (Dermatological Component)

Start date: January 2017
Phase:
Study type: Observational [Patient Registry]

To determine the relationships of dietary factors with the subsequent risk of dermatological diseases (such as skin cancers and inflammatory or autoimmune dermatoses) in a cohort of female registered nurses and male health professionals.

NCT ID: NCT03252730 Completed - Dermatitis, Atopic Clinical Trials

In-Use Test With a Cosmetic Product

Start date: January 30, 2017
Phase: N/A
Study type: Interventional

The aim of the study is to evaluate the tolerance of the product WO 4260 by a dermatologist. Additional objectives of this clinical in-use study are to evaluate the cosmetic features and acceptance of the product by means of a questionnaire in an interview situation and by skin hydration measurements on the scalp.

NCT ID: NCT03252340 Completed - Atopic Dermatitis Clinical Trials

Safety of ADSTEM Injection in Patients With Moderate to Severe Subacute and Chronic Atopic Dermatitis

Start date: September 19, 2017
Phase:
Study type: Observational

This study aims to evaluate safety in subjects with over moderately subacute and chronic atopic dermatitis after an intravenous injection of ADSTEM Inj. Since this is an observational study of patients participated in Phase 1 clinical trials, no drug is administered in this study.

NCT ID: NCT03250624 Completed - Atopic Dermatitis Clinical Trials

Safety and Efficacy of CD5024 0.3% Cream in Subjects With Atopic Dermatitis

Start date: November 1, 2016
Phase: Phase 2
Study type: Interventional

Exploratory, multi-centric, randomized, vehicle-controlled, investigator-blind, parallel group study, involved participants with chronic lesions of Atopic Dermatitis (AD) to evaluate the local and systemic safety of CD5024 0.3% cream over a 6-week treatment period compared to its vehicle.

NCT ID: NCT03242577 Completed - Dermatitis Clinical Trials

Micro-Technique Sampling

Start date: August 1, 2017
Phase: N/A
Study type: Observational

This is a single-center, exploratory comparative pilot study to identify the most appropriate method for microbial consortia sampling from the skin. Ten subjects are expected to complete the study at one investigative site in the United States. The study will consist of 2 visits, Visit 1 (Screening), Visit 2 (Sampling). At Visit 1, subjects will be consented and have their eligibility reviewed. Visit 1 and Visit 2 may be combined into one visit. Visit 1 will involve the informed consent process, screening, and enrollment. Visit 2 will involve sampling of eight (8) test sites on the back with three (3) different sampling methods: swabbing (2 sites/method), cup scrub (2 sites/method), and tape stripping (4 sites/method). All samples will be returned to Kimberly Clark then sent to a laboratory for analysis.

NCT ID: NCT03235024 Completed - Clinical trials for Atopic Dermatitis Eczema

Study to Determine Safety and Efficacy of B244 in Subjects With Mild to Moderate Atopic Dermatitis

Start date: January 15, 2018
Phase: Phase 2
Study type: Interventional

This is a Prospective, Vehicle Controlled, Double Blind, Multicenter, Randomized Phase II trial, comparing the effect of twice daily B244 application for 28 days vs vehicle application on treatment of mild to moderate AD

NCT ID: NCT03233529 Completed - Dermatitis, Atopic Clinical Trials

Crisaborole Ointment 2% Skin Biomarker Biopsy Study in Atopic Dermatitis

Start date: July 31, 2017
Phase: Phase 2
Study type: Interventional

This study is being conducted to characterize the mechanism of action of crisaborole ointment 2%, by evaluation of efficacy and changes in key skin biomarkers in atopic dermatitis (AD) lesions treated with crisaborole ointment 2% over vehicle, in subjects with mild to moderate AD. Two identified AD skin lesions for each subject will be treated for the first 15 days, one with crisaborole ointment 2% and one with vehicle, in a blinded manner, and biopsies for biomarker analysis will be performed on the lesions. Following completion of the blinded treatment period, subjects will start the 28 day open label period during which all AD affected skin lesions will be treated with crisaborole ointment 2% twice daily.