Mindfulness-based Stress Reduction and Cognitive Function in Stress and Aging

Depression Clinical Trial

Official title:

Mindfulness-based Stress Reduction and Cognitive Function in Stress and Aging

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01693874
• Other study ID #: AT007064
• Status: Completed
• Phase: Phase 1/Phase 2
• First received: March 29, 2012
• Last updated: July 21, 2014
• Start date: October 2011
• Est. completion date: June 2014

Study information

• Verified date: July 2014
• Source: Washington University School of Medicine
• Contact: n/a
• Is FDA regulated: No
• Health authority: Data and Safety monitoring board: Helen Lavretsky, M.D., UCLA, and Dimitris Kiossis, Ph.D., Cornell University
• Study type: Interventional

Clinical Trial Summary

The investigators are developing and then testing whether Mindfulness-Based Stress Reduction, a group-based instruction for increasing mindfulness, reduces anxiety and depressive symptoms and improves cognitive functioning in older adults.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 103
• Est. completion date: June 2014
• Est. primary completion date: June 2014
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• aged 65+

• current depressive and/or anxiety symptoms

• current depressive and/or anxiety disorder

• able to participate in behavioral study

Exclusion Criteria:

• unable to participate in study

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Anxiety Disorders
• Depression

Intervention

Behavioral:
• MBSR
Mindfulness-Based Stress Reduction
• control (health education)
health education

Locations

Country	Name	City	State
United States	University of California San Diego	San Diego	California
United States	Washington University School of Medicine	St Louis	Missouri

Sponsors (3)

Lead Sponsor	Collaborator
Washington University School of Medicine	National Center for Complementary and Integrative Health (NCCIH), University of California, San Diego

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	cognitive functioning	neuropsychological battery examining memory, executive functioning, and attention	approximately 2 months of study intervention	No
Secondary	mind-wandering	computerized task(s) of mind-wandering	2 months of intervention	No
Secondary	mindfulness	self-report plus ecological momentary assessment measurements of mindfulness (process variable).	2 months of intervention	No
Secondary	anxiety and depressive symptoms	scales of self-report anxiety and depressive symptoms from NIH PROMIS, and worry severity (Penn State Worry Questionnaire Abbreviated). also we will examine ecological momentary assessment measurements of anxiety and depressive symptoms.	2 months of intervention	No