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Effects of Antidepressant on Postsynaptic Signal Transduction in Serotonergic System of Depressed Patients

Depression Clinical Trial

Official title:
Effects of Antidepressant on Postsynaptic Signal Transduction in Serotonergic System of Depressed Patients

Clinical Trial Summary

The purpose of this study is to determine whether alteration of signal transduction components after antidepressant targeting, predict antidepressant responsiveness in advance before the appearance of the drug effects until 4~6 weeks after drug administration, or represent the clinical status of depressed patients.

Clinical Trial Description

The purpose of this study is to determine whether antidepressants effect on signal transduction in peripheral lymphocyte and to determine whether the signaling differences between drug responders and nonresponders predict the antidepressant response or represent the clinical status of depressed patients. ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01352572
Study type Interventional
Source Samsung Medical Center
Contact
Status Active, not recruiting
Phase N/A
Start date January 2002
Completion date December 2018
View Details
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