Depression Clinical Trial
Official title:
Inpatient Functional and Cognitive Assessment in Older Adults With Acute Myelogenous Leukemia
RATIONALE: Learning about physical ability and mental function over time in older patients
with acute myeloid leukemia may help doctors learn about the long-term effects of treatment
and plan the best treatment.
PURPOSE: This clinical trial is assessing physical and mental status in older patients with
newly diagnosed acute myeloid leukemia.
OBJECTIVES:
Primary
- Test the feasibility of pre-treatment, bedside assessment of functional and cognitive
status in older adults with newly diagnosed acute myeloid leukemia (AML).
Secondary
- Obtain preliminary data regarding the predictive value of pre-treatment, bedside
assessment of functional and cognitive status on overall survival, length of
hospitalization and early death.
OUTLINE: This is a prospective study.
At baseline, patients complete questionnaires including the Vulnerable Elders Survey
(functional status), the Mini-Mental Status Exam (cognition), and the Center for
Epidemiologic Studies-Depression. Patients also undergo physical function testing via the
Short Physical Performance Battery and hand grip strength. Further information parameters
are obtained by periodic medical chart reviews.
Patients are followed every 3 months for up to 2 years.
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