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Dentin Hypersensitivity clinical trials

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NCT ID: NCT02936830 Completed - Clinical trials for Dentin Hypersensitivity

Effectiveness of Nanohydroxyapetite Paste on Reducing Dentin Hypersensitivity

Start date: October 2016
Phase: Phase 4
Study type: Interventional

The aim of this study is to compare the efficacy of dentine hypersensitivity reduction using in office paste formula containing nanoHydroxyapatite with the commercially available fluoride (duraphat) and a placebo in treating hypersensitivity in a single visit.

NCT ID: NCT02931734 Completed - Dentin Sensitivity Clinical Trials

Assessment of Different Protocols for Cervical Dentin Hypersensitivity Treatment

CDH
Start date: October 2014
Phase: N/A
Study type: Interventional

The aim of this study is through a randomized clinical trial, double blind, splith-mouth, evaluate the various types of protocols and clinical efficacy in the reduction or even elimination of dentinal hypersensitivity by the agents Desensibilize KF - FGM Dental Products, Clinpro - 3M Company, Minnesota - USA, Photon Laser III - DMC, Brazil, Desensibilize KF and laser, Desensibilize KF and Clinpro, laser and Clinpro and the association of all products. Data will be collected, tabulated and submitted to statistical analysis.

NCT ID: NCT02483013 Completed - Clinical trials for Dentin Hypersensitivity

Clinical Study of the Whitening Dentifrices on Tooth Color and Sensitivity

Start date: August 2014
Phase: Phase 4
Study type: Interventional

Objective:The aim of this clinical study was to evaluate tooth color alteration (ΔE) and tooth sensitivity (TS) in patients that used two commercial brand-whitening dentifrices for four weeks. Sixty participants were selected in accordance with inclusion and exclusion criteria and randomly allocated in three groups (n=20): G1-Colgate Luminous White®, G2- Close up White Now® and G3- Sorriso® dentifrice (placebo). Then, participants received the instructions to use only the blinded supplied dentifrice and toothbrush to make the habitual oral hygiene, three times per day during four weeks. Evaluators assessed tooth color (CIEL*a*b system) and TS (VAS scale) at baseline and every week (assessment points 1, 2, 3 and 4). Two-way ANOVA and posterior Tukey and Friedman test analyzed data (α = 0.05).

NCT ID: NCT02378129 Completed - Clinical trials for Dentin Hypersensitivity

Evaluation of Dentin Hypersensitivity Using Glass Ionomer Cements

Start date: April 2, 2014
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this randomized, double-blind, split-mouth clinical trial is to evaluate and compare the desensitizing efficacies of the resin-modified glass ionomer cement ClinproTM XT (3M ESPE, Minnesota, USA) and the conventional glass ionomer cement Vidrion R (SS White, Gloucester, UK) at 2-year follow-up.

NCT ID: NCT02316080 Completed - Clinical trials for Dentin Hypersensitivity

The Effect of Desensitizing Agents in In-home or In-office Dental Bleaching

Start date: July 2011
Phase: Phase 4
Study type: Interventional

The aim of this project is to evaluate in vitro and in vivo the effect of dental bleaching agents, carbamide peroxide 16% (T1) and hydrogen peroxide 35% (T2) together with desensitizers/remineralizer agents, Sensodyne® dentifrice (D1); experimental dentifrice with 7,5% of Biosilicate micro-particles (D2); Odontis RX® dentifrice (D3); Sorriso® dentifrice (D4); Biosilicate micro-particles paste, 1:1 (D5), Desensebilize Nano P (D6), bioglass type 45S5 paste, 1:1 (D7); GC= distilled water, in the experimental groups: T1/D1; T1/D2; T1/D3; T1/D4; T1/D5; T1/D6; T1/D7; T1/GC e T2/D1; T2/D2; T2/D3; T2/D4; T2/D5; T2/D6; T2/D7; T2/GC. In the in vitro study, microhardness and roughness measurements, and images using scanning electron microscopy (SEM) will be made on samples of bovine dental enamel and dentin (4x4x3mm; n=10 per group) before and after the treatment with the bleaching gels (T1= 14 days/ 04 hours/day; T2=single session) and the desensitizers/remineralizer agents. In the clinical study, the volunteers (n=10 per group) will be evaluated regarding dentin hypersensitivity (DH), using visual analogue scale, before the beginning of the treatments (T1 and T2) and during the next 14 days (1º, 3º, 7º, 10 º e 14º days) in which the desensitizers/remineralizer agents (there´s no control group in the clinical experiments) will be applying. Data will be analysed intra and inter-group, statistically.

NCT ID: NCT01860391 Completed - Clinical trials for Dentin Hypersensitivity

Silver and Fluoride Salivary Levels After the Application of Silver Fluoride

Start date: December 2012
Phase: N/A
Study type: Interventional

The aim of the study is to measure salivary fluoride and silver levels up to 7 days post-treatment. The participants will be 6 healthy adults. They will be given a fluoride free toothpaste to use the day before the study and all during the study. 3 participants will have 6 teeth treated (Group A).3 participants will have 28 teeth treated each on the facial aspect (Group B). On day 0, the participant will be given 25 ml of de-ionized fluoride free water to swish in the mouth and spit the entire contents into a 50 ml collection tube. This will be done 3 times. On day 0, 10 minutes after the rinsing and spitting, the participant will provide a unstimulated salivary sample into a universal collection tube until 5 ml are collected. The tubes with saliva will be stored on ice and then frozen at -20oC for transfer to the lab at the University of Washington. On Day 0, Isolation and application of silver fluoride. The quadrant will be isolated with cotton rolls, and surrounding gingiva will be covered with petroleum jelly to provide additional protection. After application, participant will be given 25 ml of fluoride free water to rinse as in 1 above and water collected. This will be done 10 times. DAY 1-6 Salivary Collection Measures: Fluoride will be measured using standard fluoride electrode analysis (Martinez-Mier et al., 2011). Silver will be measured using Inductively Coupled Plasma-Mass Spectrometry (EPA 6020a Rev.1 2007) at the University of Washington

NCT ID: NCT01111474 Completed - Dentin Sensitivity Clinical Trials

Cyanoacrylate and Laser and Dentin Sensitivity

Cyano-laser
Start date: August 2008
Phase: N/A
Study type: Interventional

This study aimed to evaluate the effectiveness of two treatments for dental hypersensitivity: cyanoacrylate (Super Bonder®) compared with use of low intensity laser treatment (LILT). As the cyanoacrylate is a lower cost treatment, the hypothesis in investigation is if this product is equally effective as the laser treatment.

NCT ID: NCT00926484 Completed - Clinical trials for Dentin Hypersensitivity

Tooth Mousse and Fluoride in Dentin Hypersensitivity Treatment

Start date: January 2007
Phase: N/A
Study type: Observational

GC Tooth Mousse, a complex containing amorphous calcium phosphate (ACP) and casein phosphopeptide (CPP), is recommended in dentin hypersensitivity reduction due to its ability to block opened dentinal tubules. It acts synergistically with fluorine in slowing caries progression. Whether CPP-ACP can act synergistically with fluorine in the dentin hypersensitivity treatment is unknown. The aim of this study was to assess the effect of CPP-ACP combined with fluoride varnish in cervical dentin hypersensitivity treatment.

NCT ID: NCT00763269 Completed - Clinical trials for Dentin Hypersensitivity

The Efficacy of a Toothpaste to Reduce Sensitivity

Start date: September 2008
Phase: Phase 3
Study type: Interventional

Hypersensitivity