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Dental Caries in Children clinical trials

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NCT ID: NCT03557996 Not yet recruiting - Clinical trials for Dental Caries in Children

Discoloration of Carious Primary Teeth After Application of Silver Diamine Fluoride Versus Sodium Fluoride Varnish

Start date: December 1, 2018
Phase: Phase 4
Study type: Interventional

To assess discoloration of carious primary teeth after application of silver diamine fluoride versus sodium fluoride varnish.

NCT ID: NCT03554980 Not yet recruiting - Clinical trials for Dental Caries in Children

Application of SDF Verses NaF Varnish in Treatment of Carious Primary Teeth

Start date: December 1, 2018
Phase: Phase 4
Study type: Interventional

The aim of this study is to assess the postoperative pain after application of silver diamine fluoride versus sodium fluoride varnish in treatment of carious primary teeth.

NCT ID: NCT03516838 Completed - Clinical trials for Dental Caries in Children

Comparison of ACTIVA BioACTIVE Versus Compomer in Restoring Dental Decay in Primary Molar Teeth

Start date: January 2017
Phase: Phase 4
Study type: Interventional

A clinical trial to evaluate a filling material (ACTIVA) and compare it to a traditional filling material (compomer) to restore decayed deciduous teeth in children

NCT ID: NCT03480516 Completed - Quality of Life Clinical Trials

Comparison of Caries Arrested & Prevented Among SDF, NaF Varnish and Combination in Children

Start date: September 1, 2017
Phase: N/A
Study type: Interventional

Tooth decay is one of the most common chronic infectious disease found in children worldwide and if left untreated, is rapidly progress. Severe tooth decay in children is not only affect child's health and school performance, but also has impact on the family well-being. Oral rehabilitation in children requires time, resources and effort of dental specialists, the child and parents. Caries is a destructive condition of organic and inorganic components of the tooth structures but reversible and most importantly, preventable. Topical fluoride therapy, delivered by dentists has been effectively used to speed up the repair process as well as to strengthen the surface of intact tooth structure. Topical fluoride is available in various preparations. Regular application of sodium fluoride varnish is every three months, by far, considered as effective method in preventing new caries, particularly in the high-risk children. It has the advantage of containing therapeutic concentration of fluoride and ability to flow over and stick to the tooth surface. Whereas silver ion and relatively higher fluoride concentration in Silver Diamine Fluoride (SDF) has been shown to be the most effective in harden the decay, stop the caries progress and eliminate pathogenic bacteria. It can be hypothesize that when use in combination in school children, both reagents might have synergistic effect on arresting existing caries as well as preventing new caries.

NCT ID: NCT03478748 Completed - Clinical trials for Dental Caries in Children

The Impact of Anticipatory Guidance on Early Childhood Caries: a Quasi-experimental Study

Start date: January 2, 2015
Phase: N/A
Study type: Interventional

This study aimed to compare the impact of anticipatory guidance on the caries incidence of 2-3-year-old preschool children and their 4-6-year-old siblings, as well as on their mothers' oral health literacy, as compared to the conventional Ministry of Health (MOH) programme.

NCT ID: NCT03432728 Completed - Clinical trials for Dental Caries in Children

Salivary Antioxidant Capacity Before and After Complete Dental Rehabilitation

Start date: January 25, 2016
Phase: N/A
Study type: Observational

Salivary samples were obtained from 20 children in their fifth year of life diagnosed S-ECC and 20 age and sex matched controls. Complete dental rehabilitation under general anesthesia was performed for the 20 children with S-ECC, and follow up salivary samples were obtained one week and three months post operatively. The TAC was measured using a commercially available Oxygen Radical Absorbance Antioxidant Assay measurement kit (Zen-Bio ORACâ„¢, AMS Biotechnology, Abington UK).

NCT ID: NCT03397589 Completed - Health Behavior Clinical Trials

Coordinated Oral Health Promotion (CO-OP) Chicago

Start date: January 20, 2018
Phase: N/A
Study type: Interventional

This study assesses the impact of oral health promotion delivered by community health workers in medical clinics, Women, Infants and Children (WIC) centers, and family homes. Investigators will assess oral health behaviors in children aged 0 to 3.

NCT ID: NCT03315312 Active, not recruiting - Clinical trials for Dental Caries in Children

Occlusal Caries Management in First Permanent Molars in Child Dental Care

FISSURE
Start date: February 1, 2017
Phase: Phase 4
Study type: Interventional

Occlusal caries management in first permanent molars: a pragmatic randomized clinical trial in child dental care Aim of the present study is to evaluate the effectiveness of fissure sealants and fluoride varnish in a pragmatic randomized clinical trial and evaluate whether some specific patient groups benefit more from any particular treatment. The high risk children (having a previous caries experience at 5 years of age) from 2009, 2010 and 2011 birth cohorts (6-, 7- and 8-year-olds) from three counties (Østfold, Oppland and Hedmark) are selected. Children with at least two erupted first permanent molars in the same jaw randomly receive resin-based sealant or a fluoride varnish (Duraphat) during a routine dental examination. Children who already developed caries, had restorations or fissure sealants placed in first molars were excluded from the present study. Fluoride varnish and resin-based fissure sealants are randomly applied on contra-lateral teeth where each child serves as its own control. This study uses a natural clinical setting, where clinicians use methods and procedures that are routinely applied in public dental clinics. The study is approved by the Regional Committee for Medical Research Ethics South East (2016/2002/REK sør-øst C). Sample size calculations: Based on the assumption that 80% of the treated teeth do not get caries and that 10% difference in caries development constitutes a clinically meaningful difference, it is required to recruit 180 participants in the study for the split-mouth design. Considering a potential maximum of annual 20% drop-out rate and a 3-years follow-up, the study will need to recruit 400 participants in order to have at least 206 children at the 3 years of follow-up. Treatments are provided by either dentists or dental hygienists during routine dental examinations. Caregivers of eligible children are informed about the study, the participation is voluntary and an informed written parental consent is obtained in accordance with the directions of the Regional Committee for Medical Research Ethics. In this study, a clinician selects a random treatment for the first tooth by choosing one of the two cards, while a collateral tooth receives an alternative treatment. Subsequently, treatments provided and materials used are recorded on a treatment registration form. During this study, clinicians follow their conventional clinical procedures for applying sealants or fluoride varnish. Information on patient's caries experience and quality of oral hygiene are recorded on treatment registration form. Fluoride varnish is applied three times, at baseline, 6 months and 12 months. Caries on occlusal surfaces of first molars detected at later 24 and 36 months follow-ups will be recorded in the follow-up registration form. The main study outcome is caries occurrence on occlusal tooth surfaces.

NCT ID: NCT03311438 Completed - Dental Plaque Clinical Trials

Oral Health Intervention Program for Children With Congenital Heart Defects

Start date: September 1, 2009
Phase: N/A
Study type: Interventional

Background: Children with congenital heart defects (CHD) are reported to have poorer oral health compared with healthy children. The aim of the present study was to evaluate the effect of an intensive oral health care program among children with CHD followed from infancy to the age of five years, by comparing their oral health status at five years with a control group of children with CHD who had not received the program. Methods: In this longitudinal study, children in western Norway with a need for lifelong follow-up due to congenital heart defects were invited to participate (n=119). Children born in 2008-2011 were offered a promotive oral health intervention program from infancy to the age of five years. The outcome measures for evaluating the intervention were dental caries prevalence, dental erosion, plaque index and gingival bleeding index. The data of the intervention group were compared with cross sectional oral health data of five year old controls with CHD born 2005-2007 (already published).

NCT ID: NCT03063307 Completed - Clinical trials for Dental Caries in Children

Effectiveness of Silver Diamine Fluoride in Arresting Dental Caries

Start date: September 20, 2016
Phase: N/A
Study type: Interventional

The present study aims to evaluate, through a controlled clinical randomized study,the effectiveness of silver diamine fluoride in arresting dentin caries lesions in primary molars when compared to atraumatic restorative treatment.