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Clinical Trial Summary

The purpose of this study is to investigate whether markers of brain structure and function from MRI are associated with different levels of spatial orientation and gait parameters in people with mild cognitive impairment or dementia due to Alzheimer's disease when walking through a real world environment.


Clinical Trial Description

This is an experimental cross-sectional study which primarily aims at identifying characteristic features of spatial disorientation among people with mild cognitive impairment and dementia. The features of interest are motion and physiological related changes that occur during instances of spatial disorientation, which will be derived from wearable sensors.

Additionally, brain structure and functional connectivity changes associated with different levels of spatial orientation and gait parameters will also be investigated through resting-state functional imaging. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04387357
Study type Observational
Source University of Rostock
Contact Chimezie O Amaefule, M.Sc
Phone 0049-381-494-9478
Email chimezie.amaefule@dzne.de
Status Recruiting
Phase
Start date October 1, 2019
Completion date June 30, 2021

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