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Dementia clinical trials

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NCT ID: NCT05159869 Recruiting - Dementia Clinical Trials

User-Led Meaningful Activity and Early-Stage Dementia

Start date: January 24, 2022
Phase: N/A
Study type: Interventional

Neuropsychiatric symptoms are the most difficult, distressing, and burdensome aspects of dementia care and a catalyst for long-term care placement. Intervention studies have largely focused on helping caregivers manage these symptoms. However, little has been done with regard to persons at the earliest stages of dementia, nor have persons with dementia played a direct and active, central role in helping to design intervention studies. This study focuses on building, pilot testing, and evaluating a tailored activity plan developed with persons with early-stage dementia. The goal of the intervention is to provide persons at this early stage meaningful activities and a plan for adaptation with disease progression.

NCT ID: NCT05159661 Recruiting - Dementia Clinical Trials

Intelligent Digital Tools for Screening of Brain Connectivity and Dementia Risk Estimation in People Affected by Mild Cognitive Impairment

AI-Mind
Start date: March 1, 2021
Phase:
Study type: Observational

Every three seconds someone in the world develops dementia. There are over 50 million people worldwide living with dementia and by 2030 this figure is expected to reach 82 million. Besides time-consuming patient investigations with low discriminative power for dementia risk, current treatment options focus on late symptom management. By screening brain connectivity and dementia risk estimation in people affected by mild cognitive impairment, the European Union (EU) funded AI-Mind project will open the door to extending the 'dementia-free' period by offering proper diagnosis and early intervention. AI-Mind will develop two artificial intelligence-based digital tools that will identify dysfunctional brain networks and assess dementia risk. Personalised patient reports will be generated, potentially opening new windows for intervention possibilities.

NCT ID: NCT05159596 Completed - Alzheimer Disease Clinical Trials

In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Spanish Language Homes

Start date: September 20, 2022
Phase: N/A
Study type: Interventional

This study aims to develop, evaluate, and commercialize an in-home supportive technology that is designed to alleviate anxiety, burden, and loneliness in spousal and familial caregivers of individuals with Alzheimer's disease, other dementias, or mild cognitive impairment in Spanish language homes.

NCT ID: NCT05159583 Completed - Alzheimer Disease Clinical Trials

In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Rural Homes

Start date: August 22, 2022
Phase: N/A
Study type: Interventional

This study aims to develop, evaluate, and commercialize an in-home supportive technology that is designed to alleviate anxiety, burden, and loneliness in spousal and familial caregivers of individuals with Alzheimer's disease, other dementias, or mild cognitive impairment in rural homes.

NCT ID: NCT05159557 Completed - Alzheimer Disease Clinical Trials

In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment: Wearables

Start date: August 22, 2022
Phase: N/A
Study type: Interventional

This study aims to develop, evaluate, and commercialize an in-home supportive technology that is designed to alleviate anxiety, burden, and loneliness in spousal and familial caregivers of individuals with Alzheimer's disease, other dementias, or mild cognitive impairment by integrating wearable devices (e.g., Apple Watches).

NCT ID: NCT05158595 Completed - Clinical trials for Mild Cognitive Impairment

Exer-game Balance Training on Dementia

Start date: August 15, 2021
Phase: N/A
Study type: Interventional

Age-related cognitive impairment is a wide phenomenon. Mild cognitive impairment is a transitional stage between Dementia and normal cognition.Mild cognitive impairment (MCI) is a syndrome that has been recognized in older adults and it has become a topic of a major focus on clinical care and research. In people with this condition, there are cognitive deficits and these have adverse effects on activities of daily living . These patients cannot recognize their impairment. Mild cognitive impairment is a risk factor for dementia.

NCT ID: NCT05156073 Completed - Dementia Clinical Trials

Shared Decision Making About Medication Use for People With Multiple Health Problems

Start date: May 22, 2023
Phase: N/A
Study type: Interventional

The Shared Decision Making about Medication Use for People with Multiple Health Problems study will assess the feasibility and acceptability of a deprescribing educational intervention in primary care for patients with mild cognitive impairment or dementia and/or multiple chronic conditions (MCC), the patients' care partners, clinicians, and medical assistants. The intervention consists of the following strategies: 1) a patient/caregiver component focused on education and activation about deprescribing, and 2) a clinician component focused on increasing clinician awareness about options and processes for deprescribing in the MCI/dementia and/or MCC population. Clinicians will each be asked to participate in a single, 15-minute educational session on deprescribing, and medical residents will receive a 45-minute lecture. Patients, caregivers, clinicians, and medical assistants will participate in a single one-on-one debriefing interview.

NCT ID: NCT05155748 Completed - Dementia Clinical Trials

Deprescribing Intervention Among Nursing Home Residents With Major Neurocognitive Disorders

OptimaMedLTC
Start date: December 6, 2016
Phase: N/A
Study type: Interventional

Canadians with neurocognitive disorders often are admitted to nursing homes when their disease reaches an advanced stage. At the end of their life, they may encounter adverse symptoms related to medications they no longer need, while they should receive comfort care. This study proposes an intervention to reduce the use of inappropriate medications among residents of nursing homes with major neurocognitive disorders. For that purpose, nursing homes' nursing staff, physicians and pharmacists will receive education and tools for the review, adjustment or discontinuation of the medications that have become inappropriate for the residents. The residents' families will receive information regarding the complexity of drug treatment for elderly patients with major neurocognitive disorders and they will be kept informed about the proposed changes to their relative's medication. The intervention is expected to reduce the medication load while improving or maintaining the residents' well-being.

NCT ID: NCT05153161 Completed - Alzheimer Disease Clinical Trials

Memesto Wearable Device for Persons With Dementia

Start date: August 31, 2022
Phase: Phase 1
Study type: Interventional

An estimated 70% of the 7.2+ million people in the U.S. with Alzheimer's Disease and Alzheimer's Disease-Related Dementias experience agitation, characterized by poorly organized and purposeless psychomotor activity that diminishes their quality of life. The goal of this Small Business Innovation Research (SBIR) project is to develop a wearable therapy device that automatically senses rising agitation, and alerts caregivers while deploying calming voice and music therapy to help them avoid crisis level behavior. This device will improve health outcomes for AD/ADRD sufferers and reduce the substantial stress suffered by their caregivers.

NCT ID: NCT05151185 Active, not recruiting - Dementia Clinical Trials

Establishment of Core Competence and Training Model for Dementia Case Management

Start date: November 3, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to develop the core competence and training model for case management of dementia. This study is the second phase of the project. The first year is the establishment of the training program and the pilot-test stage. The second year is the project implementation and effectiveness evaluation stage, the intervention effectiveness evaluation of the training course for dementia case managers will be conducted.