Dementia Alzheimers Clinical Trial
Official title:
Effects of the Life Story Questionnaire on Physical Therapy Participation in Patients With Dementia: A Randomized Control Trial
The goal of this clinical trial is to see the effect of life story questionnaire (LSQ) on physical therapy participation in patients with dementia. The main question[s] it aims to answer are: 1. What is the effect of LSQ usage on physical therapy participation in people with dementia? 2. What is the effect of LSQ usage on depression in people with dementia? 3. What is the effect of LSQ usage on the quality of life in people with dementia? The researcher will compare these effects between the intervention group (usage of the Life Story Questionnaire) and the control group (no usage of the Life story questionnaire). All Participants will receive Physical therapy treatment as usual. The life Story Questionnaire will be used in the intervention group during physical therapy treatment. Life Story Questionnaire: It is developed by the Crisis Prevention Institute, which is a type of life story book for people with dementia. The LSQ allows caregivers to start conversations about topics that are important to each patient, can help establish rapport between the caregiver and patient.
Background: Dementia is characterized by a progressive decline in cognitive function. Dementia disease prevalence is substantially increased among people aged 65 years or older, with a progressive decline in memory, thinking, language and learning capacity. Although physical exercise benefits dementia patients, participation in activities is exceedingly difficult due to communication and cognitive impairments. Several studies demonstrated that life story books usage improved quality of life, depression symptoms, moods and participation in activity in people with dementia. However, these studies did not evaluate the effect of Life Story Questionnaire (LSQ) - a type of life story book - on physical therapy participation, depression symptoms, quality of life. Objectives: To evaluate the impact of LSQ on (1) participation in physical therapy using Pittsburgh Rehabilitation Participation Scale; (2) quality of life using Quality of Life - Alzheimer's Disease Scale (participant's version); and (3) depression symptoms using Cornell Scale for Depression in Dementia (CSDD). Methods: A consecutive sample of convenience of up to 60 patients with mild to moderate cognitive impairment with 44 (22 per group) completing the study will be recruited from a nursing home facility. Patients will be randomly allocated in two groups: (1) Control group, which will receive standard physical therapy care without LSQ use; and (2) Experimental group, where physical therapists will use the LSQ. Each patient's family member will receive a LSQ to complete prior to the start of the intervention. Patients' participation, quality of life and depression symptoms will be measured on day 1 and again after 3 weeks (mid-term), and 6 weeks of intervention. Quality of life and depression symptoms will also be measured 6 weeks following intervention. A licensed occupational therapist blinded to the participants' group allocation will measure all three dependent variables Statistical Analysis: Descriptive statistics including means, standard deviations, frequency counts, median, mode, variance and frequency counts will be used to assess sample demographics. The Rank Sum test will be used to assess differences in Pittsburgh Rehabilitation Participation Scale between the intervention and control group. Spearman Rank correlations will be used to determine the strength of the correlation between Mini-Mental state examination, Pittsburgh Rehabilitation Participation Scale and Quality of Life Alzheimer Disease. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05328115 -
A Study on the Safety, Tolerability and Immunogenicity of ALZ-101 in Participants With Early Alzheimer's Disease
|
Phase 1 | |
| Completed |
NCT03378245 -
Telemedicine-based, Multidisciplinary-team, Intervention to Reduce Unnecessary Hospitalizations
|
N/A | |
| Recruiting |
NCT04871698 -
On Site Sensors Monitoring Impacts of Cognitive Decline on ADLs
|
||
| Active, not recruiting |
NCT05847153 -
MASC: Reducing Stress for Caregivers
|
N/A | |
| Recruiting |
NCT04863859 -
Persons With Dementia and Their Extended Family Caregivers
|
||
| Recruiting |
NCT05529277 -
Implementing Dementia Care Management Into Routine Care in the Region Siegen-Wittgenstein
|
||
| Active, not recruiting |
NCT03631069 -
Detecting Dementia in the Retina Using Optical Coherence Tomography
|
||
| Not yet recruiting |
NCT06047340 -
Feasibility Study of Game Technology in the Early Diagnosis of Mild Cognitive Impairment and Alzheimer's Disease
|
N/A | |
| Terminated |
NCT03682874 -
Identifying Novel Aging Targets for Treatment of Delirium
|
||
| Completed |
NCT03907748 -
Home-based Family Caregiver-delivered Music and Reading Interventions for People With Dementia
|
N/A | |
| Completed |
NCT04058886 -
Telephone-delivered Mindfulness Intervention for African American Dementia Caregivers
|
N/A | |
| Not yet recruiting |
NCT05606445 -
Surface EMG to Measure Paratonia in Dementia
|
||
| Recruiting |
NCT04308512 -
Care Coordination System for People With Dementia
|
Phase 1/Phase 2 | |
| Active, not recruiting |
NCT03943641 -
Dementia Risk Prediction Model: Development and Validation
|
||
| Not yet recruiting |
NCT05245903 -
Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside
|
||
| Recruiting |
NCT03472482 -
Optical Coherence Tomography in Cerebral Amyloidosis
|
||
| Recruiting |
NCT04313582 -
Feasibility of the SmartPrompt for Improving Everyday Function in Dementia
|
N/A | |
| Recruiting |
NCT05315895 -
The Dampness Syndrome of Chinese Medicine Cohort Study
|
||
| Completed |
NCT04462029 -
A Study to Compare the Pharmacokinetics of BR4002 and BR4002-1 in Healthy Volunteers
|
Early Phase 1 | |
| Completed |
NCT04428112 -
Rural Dementia Caregiver Project
|
N/A |