Life Story Questionnaire and Physical Therapy Participation

Dementia Alzheimers Clinical Trial

Official title:

Effects of the Life Story Questionnaire on Physical Therapy Participation in Patients With Dementia: A Randomized Control Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05827276
• Other study ID #: IRB2023-103
• Status: Recruiting
• Phase: N/A
• Start date: April 26, 2023
• Est. completion date: March 30, 2024

Study information

• Verified date: April 2023
• Source: Texas Tech University Health Sciences Center
• Contact: Megha S Shah, DPT
• Phone: 770-2414526
• Email: meghashah[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The goal of this clinical trial is to see the effect of life story questionnaire (LSQ) on physical therapy participation in patients with dementia. The main question[s] it aims to answer are: 1. What is the effect of LSQ usage on physical therapy participation in people with dementia? 2. What is the effect of LSQ usage on depression in people with dementia? 3. What is the effect of LSQ usage on the quality of life in people with dementia? The researcher will compare these effects between the intervention group (usage of the Life Story Questionnaire) and the control group (no usage of the Life story questionnaire). All Participants will receive Physical therapy treatment as usual. The life Story Questionnaire will be used in the intervention group during physical therapy treatment. Life Story Questionnaire: It is developed by the Crisis Prevention Institute, which is a type of life story book for people with dementia. The LSQ allows caregivers to start conversations about topics that are important to each patient, can help establish rapport between the caregiver and patient.

Description:

Background: Dementia is characterized by a progressive decline in cognitive function. Dementia disease prevalence is substantially increased among people aged 65 years or older, with a progressive decline in memory, thinking, language and learning capacity. Although physical exercise benefits dementia patients, participation in activities is exceedingly difficult due to communication and cognitive impairments. Several studies demonstrated that life story books usage improved quality of life, depression symptoms, moods and participation in activity in people with dementia. However, these studies did not evaluate the effect of Life Story Questionnaire (LSQ) - a type of life story book - on physical therapy participation, depression symptoms, quality of life. Objectives: To evaluate the impact of LSQ on (1) participation in physical therapy using Pittsburgh Rehabilitation Participation Scale; (2) quality of life using Quality of Life - Alzheimer's Disease Scale (participant's version); and (3) depression symptoms using Cornell Scale for Depression in Dementia (CSDD). Methods: A consecutive sample of convenience of up to 60 patients with mild to moderate cognitive impairment with 44 (22 per group) completing the study will be recruited from a nursing home facility. Patients will be randomly allocated in two groups: (1) Control group, which will receive standard physical therapy care without LSQ use; and (2) Experimental group, where physical therapists will use the LSQ. Each patient's family member will receive a LSQ to complete prior to the start of the intervention. Patients' participation, quality of life and depression symptoms will be measured on day 1 and again after 3 weeks (mid-term), and 6 weeks of intervention. Quality of life and depression symptoms will also be measured 6 weeks following intervention. A licensed occupational therapist blinded to the participants' group allocation will measure all three dependent variables Statistical Analysis: Descriptive statistics including means, standard deviations, frequency counts, median, mode, variance and frequency counts will be used to assess sample demographics. The Rank Sum test will be used to assess differences in Pittsburgh Rehabilitation Participation Scale between the intervention and control group. Spearman Rank correlations will be used to determine the strength of the correlation between Mini-Mental state examination, Pittsburgh Rehabilitation Participation Scale and Quality of Life Alzheimer Disease.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: March 30, 2024
• Est. primary completion date: December 30, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 60 Years to 89 Years

Eligibility

Inclusion Criteria:

1. Patients residing at dementia facility in Texas;

2. Age 60-89 years;

3. Diagnosis of dementia disease, in mild to the moderate stage using the Mini-Mental State Examination (score between 10 -24) and

4. Attendance to physical therapy for 6 weeks.

Exclusion Criteria:

1. Unable to speak English;

2. Blindness;

3. Deafness;

4. Mini-Mental State Examination score >24 and

5. history of major psychiatric disorders such as schizophrenia and bipolar disorder requiring hospital admission within the last year.

Related Conditions & MeSH terms

• Alzheimer Disease
• Dementia
• Dementia Alzheimers

Intervention

Other:
• Life story questionnaire
Participant will receive physical therapy treatment as usual using information from Life Story Questionnaire.

Locations

Country	Name	City	State
United States	Peachtree Place (Dementia care facility)	Weatherford	Texas

Sponsors (2)

Lead Sponsor	Collaborator
Texas Tech University Health Sciences Center	Texas Tech University

Country where clinical trial is conducted

United States, 

References & Publications (28)

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Arvanitakis Z, Bennett DA. What Is Dementia? JAMA. 2019 Nov 5;322(17):1728. doi: 10.1001/jama.2019.11653. No abstract available. — View Citation

AsanoT, Wang C-W, Tsugaruva M, Ishikawa T. Effectiveness of high- frequency individual reminiscence interventions using life story books on person with dementia. British Journal of Occupational therapy. 2021:84(5):317-326.

Burks HB, des Bordes JKA, Chadha R, Holmes HM, Rianon NJ. Quality of Life Assessment in Older Adults with Dementia: A Systematic Review. Dement Geriatr Cogn Disord. 2021;50(2):103-110. doi: 10.1159/000515317. Epub 2021 Jun 24. — View Citation

BUTLER RN. The life review: an interpretation of reminiscence in the aged. Psychiatry. 1963 Feb;26:65-76. doi: 10.1080/00332747.1963.11023339. No abstract available. — View Citation

Cooney A, O'Shea E. The impact of life story work on person-centred care for people with dementia living in long-stay care settings in Ireland. Dementia (London). 2019 Oct-Nov;18(7-8):2731-2746. doi: 10.1177/1471301218756123. Epub 2018 Feb 7. No abstract available. — View Citation

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Elfrink TR, Zuidema SU, Kunz M, Westerhof GJ. Life story books for people with dementia: a systematic review. Int Psychogeriatr. 2018 Dec;30(12):1797-1811. doi: 10.1017/S1041610218000376. Epub 2018 Jul 18. — View Citation

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Gbiri CAO, Amusa BF. Progressive task-oriented circuit training for cognition, physical functioning and societal participation in individuals with dementia. Physiother Res Int. 2020 Oct;25(4):e1866. doi: 10.1002/pri.1866. Epub 2020 Aug 10. — View Citation

Hall AJ, Burrows L, Lang IA, Endacott R, Goodwin VA. Are physiotherapists employing person-centred care for people with dementia? An exploratory qualitative study examining the experiences of people with dementia and their carers. BMC Geriatr. 2018 Mar 2;18(1):63. doi: 10.1186/s12877-018-0756-9. — View Citation

Hoel V, Feunou CM, Wolf-Ostermann K. Technology-driven solutions to prompt conversation, aid communication and support interaction for people with dementia and their caregivers: a systematic literature review. BMC Geriatr. 2021 Mar 4;21(1):157. doi: 10.1186/s12877-021-02105-0. — View Citation

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Korner A, Lauritzen L, Abelskov K, Gulmann N, Marie Brodersen A, Wedervang-Jensen T, Marie Kjeldgaard K. The Geriatric Depression Scale and the Cornell Scale for Depression in Dementia. A validity study. Nord J Psychiatry. 2006;60(5):360-4. doi: 10.1080/08039480600937066. — View Citation

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Lenze EJ, Munin MC, Quear T, Dew MA, Rogers JC, Begley AE, Reynolds CF 3rd. The Pittsburgh Rehabilitation Participation Scale: reliability and validity of a clinician-rated measure of participation in acute rehabilitation. Arch Phys Med Rehabil. 2004 Mar;85(3):380-4. doi: 10.1016/j.apmr.2003.06.001. — View Citation

Machiels M, Metzelthin SF, Hamers JP, Zwakhalen SM. Interventions to improve communication between people with dementia and nursing staff during daily nursing care: A systematic review. Int J Nurs Stud. 2017 Jan;66:37-46. doi: 10.1016/j.ijnurstu.2016.11.017. Epub 2016 Nov 30. — View Citation

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Sari YM, Burton E, Lee DA, Hill KD. Current physiotherapy practice on delivering treatments for older people with dementia in Indonesia: A cross-sectional study. Physiother Res Int. 2022 Jan;27(1):e1931. doi: 10.1002/pri.1931. Epub 2021 Nov 2. — View Citation

Weyer G, Erzigkeit H, Kanowski S, Ihl R, Hadler D. Alzheimer's Disease Assessment Scale: reliability and validity in a multicenter clinical trial. Int Psychogeriatr. 1997 Jun;9(2):123-38. doi: 10.1017/s1041610297004298. — View Citation

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* Note: There are 28 references in all — Click here to view all references

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Cornell scale for depression in dementia	It is a a screening tool and assesses depression symptoms in dementia participants. Score ranges from a - unable to evaluate, 0- absent, 1- mild, 2- severe. Minimum score is 0 and maximum score is 38. Higher scores indicate greater depression.	1st week of Physical Therapy
Other	Cornell scale for depression in dementia	It is a a screening tool and assesses depression symptoms in dementia participants. Score ranges from a - unable to evaluate, 0- absent, 1- mild, 2- severe. Minimum score is 0 and maximum score is 38. Higher scores indicate greater depression.	3rd week of Physical Therapy
Other	Cornell scale for depression in dementia	It is a a screening tool and assesses depression symptoms in dementia participants. Score ranges from a - unable to evaluate, 0- absent, 1- mild, 2- severe. Minimum score is 0 and maximum score is 38. Higher scores indicate greater depression.	6th week of Physical Therapy
Other	Cornell scale for depression in dementia	It is a a screening tool and assesses depression symptoms in dementia participants. Score ranges from a - unable to evaluate, 0- absent, 1- mild, 2- severe. Minimum score is 0 and maximum score is 38. Higher scores indicate greater depression.	6 weeks following intervention of Physical Therapy
Primary	Pittsburgh Rehabilitation Participation Scale	To measure participation in physical therapy. Participation is graded as none (1), Poor (2), Fair (3), Good (4), Very good (5), and Excellent (6). Higher score indicates greater participation in physical therapy sessions.	1st week of physical therapy
Primary	Pittsburgh Rehabilitation Participation Scale	To measure participation in physical therapy. Participation is graded as none (1), Poor (2), Fair (3), Good (4), Very good (5), and Excellent (6). Higher score indicates greater participation in physical therapy sessions.	3rd week of Physical Therapy
Primary	Pittsburgh Rehabilitation Participation Scale	To measure participation in physical therapy. Participation is graded as none (1), Poor (2), Fair (3), Good (4), Very good (5), and Excellent (6). Higher score indicates greater participation in physical therapy sessions.	6th week of Physical Therapy
Secondary	Quality of life in Alzheimer's disease scale- participant's version	The quality of life in Alzheimer's disease scale rates 13 types of life domains and uses a scale of poor (1), fair (2), good (3), and excellent (4). Minimum score is 13 and maximum score is 52. Higher scores indicate better quality of life.	1st week of Physical Therapy
Secondary	Quality of life in Alzheimer's disease scale- participant's version	The quality of life in Alzheimer's disease scale rates 13 types of life domains and uses a scale of poor (1), fair (2), good (3), and excellent (4). Minimum score is 13 and maximum score is 52. Higher scores indicate better quality of life.	3rd week of Physical Therapy
Secondary	Quality of life in Alzheimer's disease scale- participant's version	The quality of life in Alzheimer's disease scale rates 13 types of life domains and uses a scale of poor (1), fair (2), good (3), and excellent (4). Minimum score is 13 and maximum score is 52. Higher scores indicate better quality of life.	6th week of Physical Therapy
Secondary	Quality of life - Alzheimer's disease - participant's version	The quality of life in Alzheimer's disease scale rates 13 types of life domains and uses a scale of poor (1), fair (2), good (3), and excellent (4). Minimum score is 13 and maximum score is 52. Higher scores indicate better quality of life.	6 weeks following intervention of Physical Therapy

External Links

•   Life Story Questionnaire
•   Statistic software
•   Statistic software