Intermittent Versus Continuous Surface O2 During HMP of DCD Kidneys

Status Recruiting

Clinical Trial Summary

The aim of the study is to evaluate the feasibility of this bubble and surface oxygenation and to determine the optimal timing of surface oxygenation (continuous versus intermittent) as alternative for membrane-oxygenated kidneys, originating from DCD donors, during HMP on early graft function in clinical practice.

Clinical Trial Description

Kidneys originating from deceased donors after circulatory death (DCD), category 3 and 5 (controlled) will be preserved from procurement until transplantation on hypothermic machine perfusion conditions and prospectively randomized into 2 study groups: 1) intermittent surface oxygenation during HMP (surface oxygenation interrupted during organ transport (2-4h)(I-HMPO2 group), and 2) continuous surface oxygenation during HMP (surface oxygenation during the whole machine preservation period included organ transport)(C-HMPO2 group). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05430620
Study type	Interventional
Source	Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Contact	Tom Darius, Phd
Phone	003227642218
Email	tom.darius@saintluc.uclouvain.be
Status	Recruiting
Phase	Phase 3
Start date	March 20, 2022
Completion date	January 1, 2026

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Intermittent Versus Continuous Surface O2 During HMP of DCD Kidneys — HMPO2

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms