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Dehydration clinical trials

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NCT ID: NCT02568189 Terminated - Sepsis Clinical Trials

Utility of Ultrasound Assessment of the Inferior Vena Cava in Patients With Sepsis and Dehydration

Start date: October 1, 2015
Phase: N/A
Study type: Interventional

Conduct a randomized, controlled trial looking at how the use of ultrasound analyzing the inferior vena cava impacts the management and outcomes of pediatric emergency department patients undergoing evaluation and treatment of sepsis and gastroenteritis associated dehydration.

NCT ID: NCT02486224 Terminated - Dehydration Clinical Trials

Metabolomic Analysis of the Impacts of Hydration Status on Exercise Performance

Start date: September 2015
Phase: N/A
Study type: Interventional

Kona Deep is bottled water extracted from a depth of 3000 feet off the cost of Kona, Hawaii. Kona Deep claims that this unique source provides water that is "naturally free of pathogens, chemicals and pollutants and rich in nutrients and minerals that are readily absorbed by the body". The investigators wish to examine Kona Deep's claim that this water is "beneficial to the human body" by testing the impact of drinking Kona Deep on exercise performance and recovery. Subjects will be exercised to a safe level of dehydration and then will be rehydrated with Kona Deep water, or commercially available bottled spring water or Gatorade as controls. Subjects will perform a simple exercise to evaluate peak power performance. This measurement will be compared between rehydration methods for significant differences.

NCT ID: NCT02366923 Completed - Myopia Clinical Trials

Dehydration of Stenfilcon A Contact Lenses Versus Delefilcon A Contact Lenses

Start date: April 2015
Phase: N/A
Study type: Interventional

The study will explore in vivo lens dehydration rates across a 12hr wear period for the study lenses.

NCT ID: NCT02366910 Completed - Myopia Clinical Trials

Dehydration of Omafilcon A Contact Lenses Versus Delefilcon A Contact Lenses

Start date: March 2015
Phase: N/A
Study type: Interventional

The study will explore in vivo lens dehydration rates across a 12hr wear period for the study lenses.

NCT ID: NCT02265575 Completed - Dehydration Clinical Trials

Hylenex-Assisted Resuscitation in Kenya (HARK) Trial for the Management of Dehydration

HARK
Start date: October 2014
Phase: Phase 2
Study type: Interventional

One of the leading health issues among patients, particularly children, presenting for care in low- and middle-income countries is dehydration. When oral rehydration is not sufficient or is clinically inappropriate, rehydration often occurs intravenously. An alternative to intravenous rehydration is subcutaneous infusion and - with or without hyaluronidase enzyme (or Hylenex) - has been shown in several robust trials in high-income countries to be as effective and even safer than intravenous infusion. In this study in western Kenya, the investigators propose a first-ever randomized controlled trial to evaluate whether hyaluronidase-facilitated subcutaneous infusion can be as effective and safe as IV therapy among moderate-to-severely dehydrated patients in low- and middle-income countries.

NCT ID: NCT02263365 Terminated - Clinical trials for Dehydration, Diverting Ileostomy, Loperamide

Use of Post Operative Loperamide in Colorectal Patients After Diverting Ileostomies

Start date: October 7, 2014
Phase: Phase 3
Study type: Interventional

Dehydration post creation of a diverting ileostomy is a common and debilitating problem faced by patients undergoing ileal-anal pouch anastomoses for both inflammatory bowel disease and familial adenomatous polyposis (FAP) syndrome. Those patients with low rectal cancers or other polyposis syndromes e.g. HNPCC hereditary non polyposis colorectal cancers, may potentially have a delay in the adjuvant therapy when faced with this complication. Studies performed in this groups of patients report a readmission rate of 17-21% for dehydration. Loperamide has been shown to significantly decrease the daily volume of weight of stool in these patients. The purpose of this study is to establish whether loperamide given at 4mg three times daily for 14 days from day of discharge empirically decreases 30 days readmission rate for dehydration. The investigators hypothesize that there will be a 15% decrease from 25% to 10% in the readmission rates, that severity of dehydration will be decreased.

NCT ID: NCT02253238 Active, not recruiting - Clinical trials for Head and Neck Cancer

Sensor-Assisted Prevention of Dehydration in Head and Neck Cancer Patients

Start date: January 7, 2014
Phase: N/A
Study type: Interventional

The goal of this research study is to learn if home-use of devices to identify dehydration risk, when added to standard care, will help to lower hospitalizations and emergency room visits (and related costs) in patients with head and neck cancer. CYCORE is a software-based system that enables comprehensive collection, storage and analysis of information related to cancer research and clinical care. In this study, those in the CYCORE group use devices at home to measure their dehydration risk. This information is monitored by their clinicians. Those in the standard care group complete health based surveys, as do those in the CYCORE group.

NCT ID: NCT02249845 Recruiting - Dehydration Clinical Trials

Comparing the Diagnostic Accuracy of Clinical Dehydration Scales Among Small Children

Start date: September 2014
Phase: N/A
Study type: Observational

The assessment of clinical dehydration scales diagnostic accuracy (CDS scale, WHO scale, Gorelick scale) among small children.

NCT ID: NCT02245139 Completed - Diarrhea Clinical Trials

Surveillance Study of Acute Gastroenteritis in Hospitalized Children

SAGE
Start date: July 1, 2014
Phase: N/A
Study type: Observational [Patient Registry]

Acute gastroenteritis is a common cause of hospital admission and health office visits and have a huge burden on the economy of developing countries. The investigators proposed this observational prospective study during summer period in a community and tertiary care hospital in a rural area of Lebanon to investigate the etiologies and age distribution of admitted cases to general pediatric floor from the age of 1 month up to the age of 14 years.

NCT ID: NCT02230774 Completed - Dehydration Clinical Trials

Hydration Amongst Nurses and Doctors Oncall

HANDsOn
Start date: March 2013
Phase: N/A
Study type: Observational

The main purpose of this study is to assess and compare the hydration status of medical and nursing staff and to investigate the relationship between the hydration status, cognitive function and serum cortisol (marker of stress). We hypothesise that a significant proportion of doctors and nurses will be dehydrated at the end of their working day. Some, as in other occupations, may be dehydrated at the start of their working day. This is likely to be associated with impairment in cognitive performance at the end of the working day compared to the beginning and expected to be more pronounced after a night shift. There may be less noticeable difference amongst nursing staff given the protected break time. Dehydration and associated impairment in cognition is of important clinical value as it can impact patient care. participants will be involved in the study for two shifts (one day and one night), aiming at 15 medical and 15 surgical nurses as well as 15 medical (total 15 day and 15 night shifts from each group) and surgical doctors (total 15 day and 15 night shifts from each group). Those that do not work both day and night shifts will participate for only one shift and a new participant will be recruited until target number of shifts is achieved.