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Deep Caries clinical trials

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NCT ID: NCT05327049 Completed - Deep Caries Clinical Trials

Evaluation of the Remineralizing Effect of Aloe Vera Versus Diode Laser for Management of Deep Carious Lesions.

Start date: February 1, 2021
Phase: N/A
Study type: Interventional

The present study will be performed to evaluate: The remineralizing effect of Aloe Vera versus Diode laser on deep carious dentin after selective caries removal.

NCT ID: NCT05167123 Completed - Deep Caries Clinical Trials

Pulp Capping in Primary Molars Using TheraCal (LC)

Start date: September 1, 2019
Phase: Phase 4
Study type: Interventional

A randomized clinical trial that aims to evaluate clinical and radiographic success rates of indirect pulp capping and direct pulp capping in primary molars with reversible pulpitis using a light-cured tri-calcium silicate base material (TheraCal (LC)).

NCT ID: NCT04607395 Completed - Deep Caries Clinical Trials

Pre-operative Radiograph of Deep Carious Lesions as a Predictive Tool for Pulpal Exposure

R2
Start date: February 1, 2015
Phase:
Study type: Observational

Preserving pulpal vitality is a major challenge when excavating deep caries lesions without severe symptomatology. Pulpal exposure alters success of the treatment (dropping from 93% for indirect pulp treatment with selective excavation to 11% for direct pulpotomy) and thus prognosis of dental organ and cost-effectiveness of the treatment. The preoperative x-ray is a complementary examination which allows to estimate the depth of the carious lesion. In clinical practice, it is currently difficult to accurately measure this depth on preoperative radiographs. This lack of precision leads to a decrease in the effective capacity of the operator to predict the risk of pulpal exposure. Their interpretation is considered imprecise and is not used as a diagnostic element. The aim of this study was to determine if the use of pre-operative retroalveolar radiographs can help to predict pulpal exposure risk.

NCT ID: NCT04397094 Completed - Deep Caries Clinical Trials

Theracal Pulpotomy in Primary Molars

Start date: December 1, 2017
Phase: Phase 4
Study type: Interventional

Light cured silicate based cement (theracal LC) pulpotomy was compared to formocresol pulpotomy in primary molars.

NCT ID: NCT04265833 Completed - Deep Caries Clinical Trials

Evaluation of Three Different Pulp Capping Materials in Indirect Pulp Treatment of Primary Teeth

Start date: February 8, 2015
Phase: N/A
Study type: Interventional

The aim of this randomized, controlled, three-arm parallel-group, double-blinded clinical trial was to evaluate the clinical, radiographic, and histopathological success of three different pulp-capping materials in one-stage indirect pulp treatment of primary teeth. The study included a total of 109 patients aged 5-9 years who had primary teeth with deep carious lesions with or symptoms of irreversible pulpitis. The teeth were divided into three groups according to the pulp-capping agents: (I) Calcium hydroxide (Ca[OH]2) (control group) (n=36), (II) bioactive tricalcium silicate (Biodentine) (n=37), and (III) resin-based tricalcium silicate (TheraCal LC) (n=36). All the teeth were evaluated clinically and radiographically at postoperative months 6, 12, 18, and 24. A total of 23 primary mandibular second molars that were in their regular exfoliation period (24-40 months) were extracted and fixed in 10% formaldehyde solution. The specimens were evaluated histologically to assess the integrity of the odontoblastic layer, tertiary dentin formation and the quality of the dentin formed, severity of pulpitis, and other pulpal changes.

NCT ID: NCT04262076 Completed - Deep Caries Clinical Trials

Remineralization of Caries Affected Dentin

Start date: June 1, 2018
Phase: N/A
Study type: Interventional

Remineralization of carious affected dentin

NCT ID: NCT04052685 Completed - Dental Caries Clinical Trials

Selective Removal to Soft Dentine vs Selective Removal to Firm Dentine for Deep Posterior Caries Lesions

Start date: November 28, 2018
Phase: N/A
Study type: Interventional

Removal of infected dentin contaminated with bacteria and remaining affected dentin detected as firm is the conventional strategy for the management of cavitated caries lesions. Recently, this strategy is termed as selective removal to firm dentin (SRFD) and seems to increase the potential risk of pulp exposure or loss of pulp vitality for deep caries lesions radiographically extending ¾ of dentin tissue. Alternatively, selective removal to soft dentine (SRSD) that refers to removal of caries tissue at the periphery of the cavity to firm dentin and remaining caries tissue detected as soft or leathery in proximity with the pulp might be a less invasive excavation method for deep caries lesions to maintain pulpal health. However, information on clinical advantages or disadvantages of SRSD and SRFD excavation methods is sparse and mostly rely on studies conducted for primary teeth. Moreover, clinical trials are needed to demonstrate the combined effect of carious removal strategies and calcium silicate-based materials. The aim of this study is comparison of clinical success rates of SRSD and SRFD techniques in posterior deep caries lesions. The primary outcome of the study is comparison of clinical success of SRSD and SRFD techniques by clinical and radiographic examination after 3 months, 6 months, 1 year and 2 years. The secondary outcome of the study is to investigate whether or not calcium silicate-based materials have an effect on the success rate of the treatment.

NCT ID: NCT04005872 Completed - Deep Caries Clinical Trials

Clinical and Radiographic Evaluation of Nano Silver Fluoride Versus Calcium Hydroxide in Indirect Pulp Treatment

RCT
Start date: October 1, 2019
Phase: N/A
Study type: Interventional

The management of deep carious lesions approaching a healthy pulp is considered a challenge to the dental practitioner. The conventional treatment of deep carious lesions requires the removal of all infected and affected dentin to avoid more cariogenic activity.

NCT ID: NCT03993431 Completed - Deep Caries Clinical Trials

Influence of Luting Cement on the Clinical Outcomes of Zirconia Pediatric Crowns

Start date: July 2015
Phase: N/A
Study type: Interventional

The purpose of this split-mouth study was to compare the efficacy of using Bio-active cement versus Packable glass ionomer for cementation of posterior zirconia pediatric crowns.

NCT ID: NCT03885271 Completed - Deep Caries Clinical Trials

Outcomes of the Hall Technique and Conventional Pulp Therapy for the Management of Caries in Primary Molars

Start date: May 1, 2020
Phase: N/A
Study type: Interventional

Based on the changing understanding of carious biofilm development and caries progression, Sealing carious dentine beneath a restoration deprives the caries biofilm of nutrients and alters the environment sufficiently to slow or arrest lesion progression. This has the added benefit of avoiding pulp exposure and subsequent treatment .The evidence base supporting the biological approaches which include Hall technique has been steadily increasing in the last few years. This has given rise to a growing trend towards a biological approach by Paediatric dentists and has led to an increasing concern about the merits of conventional approach in treatment of carious primary molars .