Intensive Care Unit (ICU) Admission Decisions in the Elderly : the ICE-CUB Study

Death Clinical Trial

— IceCub  

Official title:

A Prospective Multicenter Study Examining the Criteria That Determine ICU Admission of Patients Over 80 Who Present to an Emergency Department and Evaluating the Impact of ICU Admission on Short and Mid-term Vital and Functional Outcome

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00912600
• Other study ID #: AOR 03 035
• Status: Completed
• Phase: N/A
• First received: June 2, 2009
• Last updated: July 25, 2012
• Start date: November 2004
• Est. completion date: February 2009

Study information

• Verified date: May 2009
• Source: Assistance Publique - Hôpitaux de Paris
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: French Data Protection Authority
• Study type: Observational

Clinical Trial Summary

Percentage of patients over 80 admitted in ICU varies greatly from one center to another. ICU admission criteria of older patients are scarcely described and benefit of ICU admission for those patients is uncertain. In this study, we prospectively studied old patients arriving to the emergency department of 15 French hospitals with conditions that potentially warrant ICU admission.The working hypothesis was that ICU admission was associated with a 20% decrease in six-month mortality.

Description:

This was a prospective multicenter observational cohort study of elderly individuals presenting to one of 15 emergency departments and possibly qualifying for admission to an ICU. To be included, subjects had to be aged at least 80 years and be diagnosed by the ED physician with one of 74 conditions potentially warranting ICU admission.Outcome studied are ICU eligibility as assessed by emergency and ICU physicians, hospital and six-month death and changes in functional status in the six month following emergency department visit.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 2643
• Est. completion date: February 2009
• Est. primary completion date: January 2006
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 80 Years and older

Eligibility

Inclusion Criteria:

• Age over 80

• Be assigned by the emergency physician with one of 74 conditions potentially warranting ICU admission

Exclusion Criteria:

• Patient's refusal

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Activities of Daily Living
• Death
• Patient Admission

Intervention

Other:
• Intensive Care Unit admission
Intensive Care Unit admission

Locations

Country	Name	City	State
France	Hôpital Saint-Antoine	Paris

Sponsors (2)

Lead Sponsor	Collaborator
Assistance Publique - Hôpitaux de Paris	Institut National de la Santé Et de la Recherche Médicale, France

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	ICU eligibility as assessed by emergency and ICU physicians		At the admission	No
Secondary	Hospital death		During the hospitalisation	Yes
Secondary	Change in functional status		During 6 months	No
Secondary	Six-month death		During 6 months after the end of the hospitalisation	Yes