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Cystoid Macular Edema clinical trials

View clinical trials related to Cystoid Macular Edema.

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NCT ID: NCT05832996 Completed - Clinical trials for Ocular Surface Disease

Cool vs Room-temperature Artificial Tears

Start date: March 1, 2022
Phase: Phase 4
Study type: Interventional

Background and Objective: To evaluate the efficacy of cooled versus room temperature artificial tears in reducing post intravitreal injection (IVI) ocular discomfort. Patients and Methods: Patients receiving IVI were randomized to either cooled or room temperature tears intervention groups. Both groups rated their ocular discomfort following IVI before intervention and again after administration of cooled or room temperature tears.

NCT ID: NCT05615805 Completed - Clinical trials for Diabetic Macular Edema

The Effect of Ocular Rinse Volume on Surface Irritation After Intravitreal Injections

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

This is the first randomized controlled trial looking into post-injection rinse volume of standard ophthalmic eyewash and its affect on patient comfort up to 72 hours after injections.

NCT ID: NCT05474950 Recruiting - Clinical trials for Cystoid Macular Edema

Minocycline Treatment for Cystoid Macular Edema

MINOCME
Start date: January 1, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

Cystoid macular edema (CME) is one of sight-threatening, immune-related ocular diseases. The efficacy of current treatments for CME (anti-VEGF, glucocorticoids and other agents) are limiting. Minocycline, acting as a broad-spectrum antibiotic, is among tetracycline family and recently, its immunomodulatory and anti-apoptosis function has been replied to several immune diseases and degenerative diseases. This study aims to explore the efficacy and safety of minocycline for CME.

NCT ID: NCT05337332 Recruiting - Clinical trials for Central Serous Chorioretinopathy

Results of Suprachoroidal Steroids Injections in Two Chorioretinal Diseases

Start date: April 14, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

Suprachoroidal injection is a safe way for intraocular drug delivery. It was used to treat various retinal conditions.

NCT ID: NCT05158699 Recruiting - Cataract Clinical Trials

Effectiveness of Periocular Drug Injection in CATaract Surgery

EPICAT
Start date: October 13, 2021
Phase: Phase 3
Study type: Interventional

Cystoid macular edema (CME) is a major cause of suboptimal postoperative visual acuity after cataract surgery. Topical steroidal and nonsteroidal anti-inflammatory drugs (NSAIDs) are used to prevent CME. However, noncompliance with eye drops may compromise the effectiveness of treatment. Dropless periocular drug delivery during cataract surgery may improve the outcomes and cost-effectiveness of cataract surgery, and may alleviate the burden on homecare organizations.

NCT ID: NCT05069675 Recruiting - Clinical trials for Cystoid Macular Edema

Cystoid Macular Edema After Vitrectomy for Rhegmatogenous Retinal Detachment

Start date: July 12, 2021
Phase:
Study type: Observational

To investigate the incidence of cystoid macular edema in eyes with primary rhegmatogenous retinal detachment successfully treated with vitrectomy with gas tamponade, and to evaluate the clinical variables associated with its development.

NCT ID: NCT04856670 Not yet recruiting - Diabetes Mellitus Clinical Trials

Assessing Diabetes Mellitus on Cytokine Analysis and Macular Edema Following FLACS

Start date: May 25, 2021
Phase:
Study type: Observational

The purpose of this study is to assess the effects of diabetes mellitus (DM) on anterior chamber cytokine production and postoperative macular edema in patients undergoing femtosecond laser-assisted cataract surgery (FLACS). Patients with DM routinely undergo FLACS, yet the majority of studies evaluating intraocular inflammation following femtosecond laser treatment have excluded this patient population. Importantly, DM alters the inflammatory status of the eye, which may influence the production of inflammatory mediators following femtosecond laser treatment and the development of postoperative macular edema. The results from this study will provide insight into the risks and benefits of FLACS in patients with DM.

NCT ID: NCT04527523 Terminated - Clinical trials for Cystoid Macular Edema

Descemet Membrane Endothelial Keratoplasty vs. Descemet's Stripping With Endothelial Keratoplasty vs. Descemet Stripping Only

Start date: November 21, 2020
Phase:
Study type: Observational

This study aims to evaluate and compare incidence of post-operative cystoid macular edema (CME) after Descemet Membrane Endothelial Keratoplasty (DMEK), Descemet's Stripping Automated endothelial Keratoplasty (DSEK) and Descemet Stripping Only (DSO).

NCT ID: NCT04234438 Completed - Clinical trials for Retinitis Pigmentosa

Management of Cystoid Macular Edema Secondary to Retinitis Pigmentosa Via Subliminal Micropulse Yellow Laser

SL-MPL
Start date: January 1, 2018
Phase: N/A
Study type: Interventional

Purpose: To investigate the effects of subliminal micropulse yellow laser application on central macular thickness and best corrected visual acuity in cystoid macular edema secondary to retinitis pigmentosa patients.

NCT ID: NCT04225611 Recruiting - Clinical trials for Cystoid Macular Edema

Therapeutic Contact Lens Drug Delivery System (TCL-DDS) in Patients With Recurrent Cystoid Macular Edema

ContactLens
Start date: March 15, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

The main aim of the pilot study is to determine preliminary estimates of the safety, tolerability, and comfort of a dexamethasone-eluting therapeutic contact lens drug delivery system (TCL-DDS) for the treatment of recurrent cystoid macular edema. Secondarily, feasibility of the TCL-DDS system will be investigated. 1. Safety: To establish that a topical dexamethasone delivery system has an acceptable safety profile by determining the incidence and severity of ocular adverse events, as identified by eye examination through day 28 following treatment initiation. 2. Comfort and tolerability: to establish the subject tolerability and comfort of the TCL-DDS. 3. Feasibility: To establish- that a topical dexamethasone delivery system is a feasible treatment for recurrent cystoid macular edema.