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Cystoid Macular Edema clinical trials

View clinical trials related to Cystoid Macular Edema.

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NCT ID: NCT05832996 Completed - Clinical trials for Ocular Surface Disease

Cool vs Room-temperature Artificial Tears

Start date: March 1, 2022
Phase: Phase 4
Study type: Interventional

Background and Objective: To evaluate the efficacy of cooled versus room temperature artificial tears in reducing post intravitreal injection (IVI) ocular discomfort. Patients and Methods: Patients receiving IVI were randomized to either cooled or room temperature tears intervention groups. Both groups rated their ocular discomfort following IVI before intervention and again after administration of cooled or room temperature tears.

NCT ID: NCT05615805 Completed - Clinical trials for Diabetic Macular Edema

The Effect of Ocular Rinse Volume on Surface Irritation After Intravitreal Injections

Start date: March 1, 2021
Phase: N/A
Study type: Interventional

This is the first randomized controlled trial looking into post-injection rinse volume of standard ophthalmic eyewash and its affect on patient comfort up to 72 hours after injections.

NCT ID: NCT04234438 Completed - Clinical trials for Retinitis Pigmentosa

Management of Cystoid Macular Edema Secondary to Retinitis Pigmentosa Via Subliminal Micropulse Yellow Laser

SL-MPL
Start date: January 1, 2018
Phase: N/A
Study type: Interventional

Purpose: To investigate the effects of subliminal micropulse yellow laser application on central macular thickness and best corrected visual acuity in cystoid macular edema secondary to retinitis pigmentosa patients.

NCT ID: NCT03025945 Completed - Clinical trials for Cystoid Macular Edema

Prospective Study With Adjunctive Once Daily Topical Nepafenac 0.3% Versus Placebo

Start date: October 2013
Phase: N/A
Study type: Interventional

Prospective, randomized, double-masked, placebo-controlled clinical study to define the effective use of a topical non-steroidal anti-inflammatory drug added to topical steroid use after uncomplicated phacoemulsification for the prevention of pseudophakic cystoid macular edema.

NCT ID: NCT02609165 Completed - Clinical trials for Retinitis Pigmentosa

Nerve Growth Factor Eye Drops Treatment in Patients With Retinitis Pigmentosa and Cystoid Macular Edema

NEMO
Start date: May 2015
Phase: Phase 2
Study type: Interventional

This study aims at investigating the therapeutic potential of recombinant human Nerve Growth Factor ( rhNGF ) eye drops treatment in patients with Retinitis Pigmentosa (RP) associated with cystoid macular edema (CME) in a phase II, randomized, double-masked, controlled clinical trial.

NCT ID: NCT02392364 Completed - Clinical trials for Diabetic Macular Edema

Variable Interval Versus Set Interval Aflibercept for DME

EVADE
Start date: April 15, 2015
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the safety and efficacy of intravitreal Eylea injections at a set interval, versus a variable dosing schedule (likely longer than one month), based on a specific individual's disease progression. There will be approximately 50 men and women at least 18 years of age, diagnosed with type 1 or type 2 diabetes, taking part in this study at 5 locations in the United States.

NCT ID: NCT02294656 Completed - Clinical trials for CYSTOID MACULAR EDEMA

Acute Pseudophakic Cystoid Macular Edema Treatment Trial: Intravitreal Ranibizumab Versus Triamcinolone Acetonide

Start date: November 2014
Phase: Phase 1
Study type: Interventional

This is an open-label, Phase I/II study evaluating intravitreal ranibizumab (R) vs. intravitreal Triesence (triamcinolone acetonide) (T) in subjects with acute pseudophakic cystoid macular edema (CME). Twenty consented patients with acute CME after phacoemulsification cataract surgery with posterior chamber intraocular lens implantation (PE/PCIOL) will be randomized 1:1 to treatment with R or T. R patients will receive three monthly R injections, followed by PRN dosing. T patients will receive PRN injections every 3 months. Clinical CME is defined as clinically evident CME, with visual acuity (VA) typically in the 20/40 to 20/200 range. Re-treatment criteria will include clinically evident worsening of CME, combined with any of the following: - Any increase in spectral domain ocular coherence tomography (OCT) central macular thickness (CMT) - Any observable fluid on OCT - Any qualitatively increased perifoveal leakage/pooling on fluorescein angiography (FA). Patients will be followed monthly through 12 months.

NCT ID: NCT02084576 Completed - Cataract Clinical Trials

Anti-inflammatory Efficacy for Prophylaxis of Cystoid Macular Edema (CME) After Phacoemulsification

Start date: August 2013
Phase: Phase 4
Study type: Interventional

To compare the anti-inflammatory efficacy of ketorolac of tromethamine 0.4% and nepafenac 0.1% eye drops for prophylaxis of cystoid macular edema (CME) after small-incision cataract extraction.

NCT ID: NCT01978015 Completed - Clinical trials for Cystoid Macular Edema

Blood-aqueous Barrier Changes After the Use of Timolol and Prostaglandin Analogues Fixed Combination in Pseudophakic Patients With POAG

Start date: October 2011
Phase: Phase 4
Study type: Interventional

Glaucoma, a progressive optic disc neuropathy causing visual field reduction, is the second leading cause of world blindness. The treatment of glaucoma is mainly based in reducing intraocular pressure (IOP) with topical medications. Many patients required two or more medications to achieve a target IOP. Combinations of B-blockers and prostaglandin analogs (PGA) are frequently used in clinical practice because their additive effect in lowering IOP levels. The aim of this study was to investigate the effects of fixed combinations of timolol maleate and PGA on the blood-aqueous barrier and evaluate the measurement of foveal thickness in pseudophakic patients with primary open-angle glaucoma (POAG).

NCT ID: NCT01774474 Completed - Diabetes Mellitus Clinical Trials

PRevention of Macular EDema After Cataract Surgery

PREMED
Start date: July 10, 2013
Phase: Phase 3
Study type: Interventional

Cystoid macular edema (CME) is a common cause of vision loss after cataract surgery. In the last few years, several new treatments have been tried to address the problem of CME after cataract surgery in diabetic and non-diabetic patients. The investigators will perform a large RCT with the aim to provide more definite evidence-based recommendations for clinical guidelines to prevent the occurrence of CME after cataract surgery in patients with and without diabetes mellitus (DM).