Thoracic Epidural Analgesia Versus Rectus Sheath Block Versus Surgeon Infiltration With Liposomal Bupivacaine or Standard Bupivacaine for Post-Operative Pain Control After Cystectomy

Cystectomy Clinical Trial

Official title: Thoracic Epidural Analgesia Versus Rectus Sheath Block Versus Surgeon Infiltration With Liposomal Bupivacaine or Standard Bupivacaine for Post-Operative Pain Control After Cystectomy

Status Active, not recruiting

Clinical Trial Summary

The purpose of this study is to compare the difference between four different pain control methods in patients who will be having a cystectomy surgery (surgical removal of the bladder).

Clinical Trial Description

The purpose of this study is to compare the difference between four different pain control methods in patients who will be having a cystectomy surgery (surgical removal of the bladder). By collecting this data, we aim to show improved postoperative pain scores, decreased opioid needs, and decreased opioid side effects (feeling sick to your stomach, feeling drowsy/sleepy, blockage/lack of movement in the intestines, inability to completely empty the bladder, unusually slow or shallow breathing).

The specific aim of this study is to compare the difference between the pain control methods in achieving the following:

1. Decreased opioid requirements

2. Improved postoperative VAS pain scores

3. Decreased opioid side effects (Nausea, sedation, ileus, respiratory depression)

4. Decreased hospital length of stay (LOS) ;

Related Conditions & MeSH terms

• Cystectomy
• Pain, Postoperative

• NCT number: NCT04300231
• Study type: Interventional
• Source: Indiana University
• Status: Active, not recruiting
• Phase: Phase 3
• Start date: October 22, 2019
• Completion date: June 30, 2023