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Clinical Trial Summary

Prospective cohort study of COVID-19 infection among children in Norway.


Clinical Trial Description

This nation-wide, prospective cohort study of COVID-19 infection addresses three main issues: 1) Epidemiological risk factors; 2) Natural history (including immunological mechanisms and long term effects) and 3) Support of infection prevention. Also, the study focuses solely on children. Children (0-18 years of age) admitted to hospital with suspected COVID-19 are eligible (Fig. 1). Those with confirmed COVID-19 serve as cases, whereas those with non-COVID-19 serve as controls; both groups will be followed prospectively for 6 months. Three objectives/Work Packages (WPs) are defined: - In WP1, the investigators will investigate risk factors for severe outcome of the acute infection; potential risk factors include sex, age, comorbidities, initial clinical findings, infectious load, and genetic markers. - In WP2, the investigators will investigate the immunological response to acute infection, focusing on initial innate host response and its associations to inflammatory enhancement, genetic factors and clinical course. - In WP3, the investigators will investigate the prevalence and risk factors of long-lasting complication, in particular the development of post-infectious chronic fatigue ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04335773
Study type Observational [Patient Registry]
Source University Hospital, Akershus
Contact Christopher Inchley, Phd
Phone 90069276
Email chris.inchley@gmail.com
Status Recruiting
Phase
Start date April 3, 2020
Completion date December 31, 2030

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