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Clinical Trial Summary

COVID-19 can trigger a dysregulated immune response, and previous studies have shown that immune modulation can improve outcomes in hospitalized patients. This trial is designed to determine whether intensification of immune modulation early in the course of the disease (while patients are on low flow oxygen) with abatacept (active arm) combined with standard of care (SOC) improves recovery as compared with placebo + SOC (placebo arm). For both groups, intensification of immunomodulation will be provided as part of SOC in case of signs of disease progression (patient requires high flow nasal oxygen (HFNO) or more support) and/or if the patient has rapidly increasing oxygen requirement.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05822583
Study type Interventional
Source University of Minnesota
Contact Cavan Reilly, PhD
Phone 612-624-9644
Email webe0376@umn.edu
Status Recruiting
Phase Phase 4
Start date July 6, 2023
Completion date July 1, 2025

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