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Clinical Trial Summary

COVID-19 has swept the world, and while some people may experience long-term cognitive decline as a result of infection, no effective treatment has been announced. The primary goal of this study was to determine the efficacy of hyperbaric oxygen therapy in patients with SARS-CoV-2 infection, as well as to assess the effect of hyperbaric oxygen therapy on brain function in patients with COVID-19-related cognitive decline. In this study, approximately 80 people were randomly assigned to either hyperbaric oxygen or regular oxygen therapy to compare the effects of these two treatments on disease.


Clinical Trial Description

80 patients with cognitive impairment following a novel coronavirus infection will be randomly assigned to one of two treatment groups: hyperbaric oxygen therapy or conventional oxygen therapy. After the intervention, the improvement of hyperbaric oxygen on cognition, fatigue, sleep disorders, anxiety and depression, and other clinical manifestations was observed. The neurologic function of hyperbaric oxygen in the treatment of patients with cognitive decline after SARS-CoV-2 infection was also evaluated from imaging and electrophysiological multi-dimensional indexes. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05715801
Study type Interventional
Source The First Affiliated Hospital of Zhejiang Chinese Medical University
Contact Yan Jiang, M.D.
Phone 13575757710
Email jiangyan@zcmu.edu.cn
Status Not yet recruiting
Phase N/A
Start date January 29, 2023
Completion date January 31, 2024

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