COVID-19 Clinical Trial
Official title:
Lung and Diaphragm Ultrasound Evaluation During Weaning From Mechanical Ventilation in COVID-19 Patients:A Prospective, Observational Study
NCT number | NCT05706441 |
Other study ID # | 2023-0017 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | January 11, 2023 |
Est. completion date | March 30, 2023 |
Verified date | January 2023 |
Source | Second Affiliated Hospital, School of Medicine, Zhejiang University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
The goal of this observational study is to learn about the function of lung and diaphragm ultrasound during weaning from mechanical ventilation in COVID-19 patients. The aim of this study was that the lung ultrasound score and diaphragm muscle mobility could be a potential predictive factor of weaning success.
Status | Completed |
Enrollment | 35 |
Est. completion date | March 30, 2023 |
Est. primary completion date | March 30, 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - age > 18 years, - critically ill patients with COVID-19 (defined as those requiring mechanical ventilation due to respiratory failure), and eligible for their first SBT according to the attending physician's judgement that the underlying disease which led to intubation had sufficiently resolved. Exclusion Criteria: - patients with previous cardiothoracic surgery or pleurodesis and patients who presented with stridor (due to upper airway involvement) as a cause of extubation failure - neuromuscular disease |
Country | Name | City | State |
---|---|---|---|
China | The Second Affiliated Hospital of Zhejiang University anesthesiology department | Hangzhou | Zhejiang |
Lead Sponsor | Collaborator |
---|---|
Second Affiliated Hospital, School of Medicine, Zhejiang University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | The primary end-point was to verify the lung and diaphragm ultrasound evaluation if the predicts weaning success/failure from mechanical ventilation | Weaning failure was defined as failure to pass the spontaneous-breathing trial or the need for re-intubation within 48 h following extubation | spontaneous-breathing trial started until 48 hours following extubation | |
Secondary | The secondary outcome was to verify the predictive value of the traditional weaning parameters | Weaning failure was defined as failure to pass the spontaneous-breathing trial or the need for re-intubation within 48 h following extubation | spontaneous-breathing trial started until 48 hours following extubation |
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