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Efficacy and Safety of COVID-19 Vaccine as Booster Vaccination in Adults 18 Years of Age or Older

COVID-19 Clinical Trial

Official title:
A Multicentre, Randomized, Double-blinded, Placebo-controlled Phase III Clinical Trial to Evaluate the Efficacy and Safety of Recombinant SARS-CoV-2 Vaccine (CHO Cell) LYB001 as Booster Vaccination in Adults 18 Years of Age or Older

Clinical Trial Summary

This is an international multicenter clinical trial, which is planned to be conducted in several research centers in China and Pakistan. A randomized, double-blind, placebo-controlled design will be conducted to evaluate the efficacy, safety of LYB001 against COVID-19 as a booster dose in China.

Clinical Trial Description

3000 subjects aged 18 years and older who have completed two or three doses of SARS-CoV-2 inactivated vaccine 6-18 months will be enrolled in China. Participants are randomly assigned to LYB001 or placebo group at a ratio of 1:1 and receive one dose at day 0. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05683600
Study type Interventional
Source Guangzhou Patronus Biotech Co., Ltd.
Contact
Status Terminated
Phase Phase 3
Start date December 29, 2022
Completion date July 12, 2023
View Details
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