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Clinical Trial Summary

This trial is being completed to understand whether people with a history of an adverse reaction to the first or second dose of either the Pfizer-BioNTech COVID-19 vaccine or the Moderna COVID-19 vaccine can safely tolerate an additional dose or if individuals with a personal history of allergic reaction who declined COVID-19 vaccination administration can safely tolerate an initial dose. Eligible participants enrolled in this trial will receive an initial or additional dose of either the Pfizer-BioNTech COVID-19 vaccine or the Moderna COVID-19 vaccine. Participants will also be required to have 1-2 in person visits along with phone call follow up visits. The study hypothesizes that individuals that have had adverse reactions to a dose of an mRNA COVID-19 vaccine will tolerate an additional dose and those with a personal history of allergic reaction will tolerate vaccination with an mRNA COVID-19 vaccine.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05212610
Study type Interventional
Source University of Michigan
Contact Charles Schuler IV, MD
Phone 734-936-5634
Email [email protected]
Status Recruiting
Phase Phase 4
Start date March 21, 2022
Completion date December 30, 2024

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