Covid19 Clinical Trial
Official title:
Association of the Neutrophil/Lymphocyte Ratio and Lymphocyte/Platelet Ratio With Pulmonary Complications and Mortality in COVID-19 Patients
NCT number | NCT05052346 |
Other study ID # | NR-09-2020 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | March 30, 2020 |
Est. completion date | May 15, 2020 |
Verified date | September 2021 |
Source | Hospital General de Mexico |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational [Patient Registry] |
The Coronavirus Disease-19 (COVID-19) pandemic is currently a priority for health services worldwide. Unlike the Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV) epidemic in 2012, the COVID-19 shows specific alterations in the white blood cell count, accentuated in severe cases, and with respiratory failure. Among the most relevant data are both lymphopenia, thrombocytopenia, and eosinopenia. The Neutrophil Lymphocyte Index has been beneficial in the evaluation of infectious respiratory processes, showing a sensitivity similar to scales such as CURB65 (Confusion, Uremia, Respiratory rate, BP, age ≥ 65 years). Because COVID-19 infection shows alterations in the blood cell ratio, these indices may be useful in evaluating patients with COVID-19 infection.
Status | Completed |
Enrollment | 200 |
Est. completion date | May 15, 2020 |
Est. primary completion date | May 5, 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 80 Years |
Eligibility | Inclusion Criteria: - Patients with active COVID-19 infection Exclusion Criteria: - Liver failure - Active cancer - Chronic renal failure - AIDS - Pregnancy |
Country | Name | City | State |
---|---|---|---|
Mexico | Omar Ramos-Peñafiel | Mexico City |
Lead Sponsor | Collaborator |
---|---|
Hospital General de Mexico |
Mexico,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Respiratory Complications in COVID-19 patients | To assess the relationship of the Neutrophil-Lymphocyte and Lymphocyte-Platelet index on respiratory complications | 6 months | |
Primary | Mortality in COVID-19 patients | To assess the relationship of the Neutrophil-Lymphocyte and Lymphocyte-Platelet index on respiratory complications | 6 months |
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