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Clinical Trial Summary

A randomized, double-blind, placebo-controlled, adaptive, seamless phase I / II clinical study of the safety and immunogenicity of a recombinant viral vector AAV5-RBD-S vaccine for the prevention of coronavirus infection (COVID-19)


Clinical Trial Description

The study will be carried out in 2 stages. Stage 1 aims to assess the safety and immunogenicity of different doses of BCD-250 in subjects without a history of COVID-19 infection to choose the optimal dose for further investigation. Stage 2 aims to assess the immunogenicity and safety of the chosen on stage 1 optimal BCD-250 dose compared to placebo in subjects with and without the history of COVID-19 infection. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05037188
Study type Interventional
Source Biocad
Contact Anton Lutckii, MD, PhD
Phone +7 (812) 380 49 33
Email [email protected]
Status Recruiting
Phase Phase 1/Phase 2
Start date August 10, 2021
Completion date December 2022

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