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NCT04834947 Clinical Trial

Hemodynamic Effect of Prone Position in Non-intubated Patient With COVID 19

Covid19 Clinical Trial

Official title:
Hemodynamic Effect of Prone Positioning in Non-intubated Patient With COVID 19 Pneumonia: a Monocentric Prospective Cohort Study

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT04834947
Other study ID # 69HCL21_0063
Secondary ID
Status Not yet recruiting
Phase
First received
Last updated
Start date April 15, 2021
Est. completion date December 15, 2021

Study information
Verified date March 2021
Source Hospices Civils de Lyon
Contact Matthias JACQUET LAGREZE, MD
Phone 0033472318933
Email matthias.jacquet-lagrèze@chu-lyon.fr
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Prone position in non-intubated patient has shown some respiratory physiological benefits. Prone positioning in patient intubated with ARDS has shown hemodynamic benefits. We aim to compare hemodynamic assessment before and after prone positioning in non-intubated patient with COVID 19 pneumonia. The study hypothesis is that prone positioning in non-intubated patient improve right ventricular preload, reduce afterload and increase Cardiac index compared to supine position.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 30
Est. completion date December 15, 2021
Est. primary completion date December 15, 2021
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Adult patient - COVID 19 pneumonias with Hypoxemia - for whom prone positioning has been decided by the attending physician. Exclusion Criteria: - Mechanical ventilation - ECLS

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• prone position
Choice of prone positioning a patient is at the discretion of the anesthesia physician.

Locations
Country Name City State
France Service d'Anesthésie-Réanimation, Hôpital Louis Pradel, Bron

Sponsors (1)
Lead Sponsor Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary Hemodynamic effect Cardiac index Cardiac index will be recorded before, just after prone position and after return to supine position.
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