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Clinical Trial Summary

This retrospective cohort study aims to evaluate the effect of proton pump inhibitor (PPI) or histamine-2 receptor antagonist (H2RA) on the clinical outcomes and positivity rates of Coronavirus Disease-19 (COVID-19).


Clinical Trial Description

Previous researches on the association between the use of PPI and H2RA and the treatment and prevention of COVID-19 have reported inconsistent findings. This study aimed to evaluate the effect of H2 receptor antagonists and proton pump inhibitors on the clinical outcomes and positivity rates of COVID-19 using the Korean National Health Insurance (NHI) data. This is a retrospective cohort study using the NHI COVID-19 dataset, which includes health insurance data of individuals who underwent COVID-19 PCR test in South Korea. This study aims to evaluate the effect of the use of PPI and H2RA on the positivity rates and clinical outcomes of COVID-19. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04834752
Study type Observational
Source Seoul National University Hospital
Contact Bokyung Kim, M.D.
Phone +82-2-2072-8112
Email lovebkim1119@naver.com
Status Not yet recruiting
Phase
Start date May 1, 2021
Completion date December 31, 2021

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