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NCT04799873 Clinical Trial

Alpha-1-Antitrypsin-Deficiency in COVID-19

Covid19 Clinical Trial

— CORSAAR-AAT  

Official title:
Individual Treatment of COVID-19 by Application of Alpha-1-antitrypsin

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04799873
Other study ID # CORSAAR-AAT-001
Secondary ID
Status Completed
Phase
First received
Last updated
Start date April 8, 2020
Est. completion date December 1, 2020

Study information
Verified date March 2021
Source Universität des Saarlandes
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The blood concentrations of alpha-1-antitrypsin are monitored during COVID-19. The clinical course of patients that received AAT infusion for clinical indication is monitored.

Description:

The blood concentrations of alpha-1-antitrypsin are monitored during COVID-19. The clinical course of patients that received AAT infusion for clinical indication is monitored. Clinical outcomes, blood inflammatory markers, and virus load are monitored.

Recruitment information / eligibility
Status Completed
Enrollment 10
Est. completion date December 1, 2020
Est. primary completion date December 1, 2020
Accepts healthy volunteers No
Gender All
Age group 18 Years to 110 Years
Eligibility Inclusion Criteria: - Infection with SARS-COV2 - Age over 18 years Exclusion Criteria: - Unability to consent - Invasive ventilation

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• AAT( Alpha 1 Antitrypsin)
AAT administration based on clinical indication

Locations
Country Name City State
Germany Saarland University Homburg Saarland

Sponsors (1)
Lead Sponsor Collaborator
Universität des Saarlandes

Country where clinical trial is conducted

Germany, 

Outcome
Type Measure Description Time frame Safety issue
Primary Clinical course Disease course such as death, need for ICU treatment, ventilatory support or deterioration are monitored 3 months
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