COVID19 Clinical Trial
Official title:
The Effect of the Severity of COVID-19 Disease on the Incidence of Acute Renal Failure in ICU
NCT number | NCT04799600 |
Other study ID # | E1-20-1443 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | September 1, 2020 |
Est. completion date | July 1, 2021 |
Verified date | July 2021 |
Source | Ankara City Hospital Bilkent |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Aim of the study is to determinate the frequency of acute renal failure in COVID-19 patients, its relationship with the severity of COVID-19 disease in ICU, and the ability to take precautions against these factors.
Status | Completed |
Enrollment | 158 |
Est. completion date | July 1, 2021 |
Est. primary completion date | June 15, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | N/A and older |
Eligibility | Inclusion Criteria: Patients hospitalized in the intensive care unit diagnosed with COVID-19 will include in the study. Exclusion Criteria: there is no exclusion criteria |
Country | Name | City | State |
---|---|---|---|
Turkey | Ankara City Hospital | Ankara |
Lead Sponsor | Collaborator |
---|---|
Ankara City Hospital Bilkent |
Turkey,
Kellum JA, Lameire N; KDIGO AKI Guideline Work Group. Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1). Crit Care. 2013 Feb 4;17(1):204. doi: 10.1186/cc11454. Review. — View Citation
Rodriguez-Nava G, Yanez-Bello MA, Trelles-Garcia DP, Chung CW, Friedman HJ, Hines DW. Performance of the quick COVID-19 severity index and the Brescia-COVID respiratory severity scale in hospitalized patients with COVID-19 in a community hospital setting. — View Citation
Wang L, Li X, Chen H, Yan S, Li D, Li Y, Gong Z. Coronavirus Disease 19 Infection Does Not Result in Acute Kidney Injury: An Analysis of 116 Hospitalized Patients from Wuhan, China. Am J Nephrol. 2020;51(5):343-348. doi: 10.1159/000507471. Epub 2020 Mar 3 — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | KDIGO criteria | KDIGO Criteria stage 1: Increase in SCr by = 0.3 mg/dL within 48 hours or increase in SCr 1.5 to 1.9 times baseline which is known or presumed to have occurred within the prior 7 days Stage 2: 2.0 to 2.9 multiplied by baseline SCr;
Stage 3: 3.0 or more multiplied by baseline; increase in SCr = 4.0 mg/dL; or beginning of renal replacement therapy regardless of a previous KDIGO stage. |
6 months | |
Primary | BRESCIA-COVID RESPIRATORY SEVERITY SCALE (BCRSS) scores | The BCRSS score (between level 0-8) is calculated from "www.mdcalc.com/brescia-covid-respiratory-severity-scale-bcrss-algorithm" according to the severity of COVID disease , respiratory rate, PaO2 level, chest x-ray, and clinical status. | 6 months |
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