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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT04734223
Other study ID # 09.25.2020/587
Secondary ID
Status Completed
Phase
First received
Last updated
Start date April 1, 2020
Est. completion date December 31, 2020

Study information

Verified date February 2021
Source Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This study aimed to discuss the neuroimaging findings and indications, epidemiological data, laboratory values, and the relationship of these variables with mortality in patients with COVID-19.


Description:

COVID-19 can present as neurological symptoms such as anosmia, headache, taste perversion, dizziness, syncope, and altered state of consciousness. It has been reported in previous studies that thromboembolic ischemic and hemorrhagic strokes associated with COVID-19 have been observed in the early period. It has been suggested that conditions characterized by neurological sequelae, such as encephalitis and encephalopathy, ataxic seizures, Guillain-Barré syndrome (GBS), demyelinating diseases, and neuromuscular disorders may occur in the longer term.In the present study, the investigators aimed to reveal the findings of neuroimaging analyses performed in patients followed up with a diagnosis of COVID-19 who had neurological symptoms, discuss the relationship of these findings with laboratory and epidemiological data, and emphasize that CNS involvement in these patients should not be overlooked. In this study, 436 patients with COVID-19 who underwent at least one neuroimaging procedure during April 2020-December 2020 due to neurological symptoms and whose diagnosis was confirmed by reverse transcriptase-polymerase chain reaction test were included. Although computed tomography was predominantly used for imaging, magnetic resonance imaging was also used when necessary. The patients were grouped based on imaging findings, and statistical evaluations were made between the groups.


Recruitment information / eligibility

Status Completed
Enrollment 436
Est. completion date December 31, 2020
Est. primary completion date December 31, 2020
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - COVID-19 RT-PCR positivity- - older than 18 years old Exclusion Criteria: - younger than 18 years old

Study Design


Related Conditions & MeSH terms


Intervention

Diagnostic Test:
Neuroimaging Findings in Patients With COVID-19
MR and BT Imaging

Locations

Country Name City State
Turkey Saglik Bilimleri Üniversitesi Training and Research Hospital Di?yarbakir

Sponsors (1)

Lead Sponsor Collaborator
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type Measure Description Time frame Safety issue
Primary Frequency of acute thromboembolism in COVID-19 patients undergoing neuroimaging Acute thromboembolic events are common in COVID-19 subjects undergoing neuroimaging, potentially due to an increased procoagulant process. Between April and December 2020
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