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NCT04716569 Clinical Trial

Evaluation of Ivermectin Mucoadhesive Nanosuspension as Nasal Spray in Management of Early Covid-19

Covid19 Clinical Trial

Official title:
Faculty of Medicine ,South Valley University

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04716569
Other study ID # SVU MED CIT0 23 4 21 1 120
Secondary ID
Status Recruiting
Phase Phase 2/Phase 3
First received
Last updated
Start date January 20, 2021
Est. completion date March 20, 2021

Study information
Verified date March 2021
Source South Valley University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Ivermectin showed a strong viricidal effect upon covid19 virus in vitro as proved by many authors according to many studies , covid virus stay in postnasal space for 4 days before starting general manifestation, so ivermectin mucoadhesive nanosuspension sprayed inside the nose and post nasal space may help in early management of covid19 and may play a great rule in prophylaxis as well

Description:

150 patient with early covid is devided into two groups first group will receive regular protocol of drugs second group will receive ivermectin nasal spray in addition to regular protocl of drugs

Recruitment information / eligibility
Status Recruiting
Enrollment 150
Est. completion date March 20, 2021
Est. primary completion date February 20, 2021
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - early covid19 pateints Exclusion Criteria: - children and pregnant women

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• intranasal ivermectin spray
usage of ivermectin as intranasal spray for treating early covid patiens

Locations
Country Name City State
Egypt Zaky Aref Qina Qina

Sponsors (1)
Lead Sponsor Collaborator
South Valley University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary progression of covid 19 clinical picture progress of Symptoms ( Fever ,Cough, Sore Throat, Myalgia,Diarrhea, Shortness of Breath)with radiological assesment and blood tests [ Time Frame: within 14 days after enrollement ]
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