Effect of Prone Positioning in Patients With COVID-19

Covid19 Clinical Trial

Official title:

Effect of Prone Positioning and Alternate Nostril Breathing Technique in Patients With COVID-19: A Prospective Cohort Study.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04710771
• Other study ID #: 138
• Status: Completed
• Start date: November 23, 2020
• Est. completion date: January 29, 2021

Study information

• Verified date: February 2021
• Source: Sialkott College of Physical Therapy
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

COVID-19 is affecting the people around the world and the infected individuals' may either stay asymptomatic or present to hospitals with severe distress and life threatening symptoms. The objective of the study is to investigate role of Prone positioning and alternate nostril breathing in patients with Covid-19.

Description:

In this prospective study, 30 patients aged 40-80 years of either gender with a confirmed diagnosis of COVID-19 receiving supplemental oxygen were recruited from DHQ Hospital Faisalabad. patients were grouped into two A & B. We collected baseline data on demographics and anthropometrics. After baseline data collection, all the patients were helped into the prone position, which was maintained for a minimum duration of three hours. After that patients in group B performed alternate nostril breathing for 10 minutes with help of therapist. Clinical data were re-collected on 3rd day of intervention one hour after returning to the supine position in group A and after alternate nostril breathing in group B. The main study outcome was the variation in oxygenation (partial pressure of oxygen [PaO2]/ fractional concentration of oxygen in inspired air [FiO2]) between baseline and resupination, and General psychological state through GAD-7 General anxiety disorder questionnaire.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: January 29, 2021
• Est. primary completion date: January 15, 2021
• Accepts healthy volunteers: No
• Gender: All
• Age group: 40 Years to 80 Years

Eligibility

Inclusion Criteria:

Age: 40-80 Gender: Both GCS score:15

Exclusion Criteria:

• COPD Intubated ARDS Smoker Neurological Disorder

Related Conditions & MeSH terms

• Covid19

Intervention

Other:
• Prone Lying Position
patient lies on his/ her stomach facing floor.
• alternate nostril breathing
patient inspires with one nostril at a time, right or left one by one and expires by mouth.

Locations

Country	Name	City	State
Pakistan	DHQ Hospital	Faisalabad	Punjab

Sponsors (1)

Lead Sponsor	Collaborator
Sialkott College of Physical Therapy

Country where clinical trial is conducted

Pakistan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	PaO2	partial pressure of oxygen.	Change in score before the intervention on 1st day of intervention and on 3rd day one hour after the intervention.
Primary	FiO2	Fractional concentration of oxygen in inspired air [FiO2])	Change in score before the intervention on 1st day of intervention and on 3rd day one hour after the intervention.
Primary	General Anxiety Disorder-7 Score	general anxiety disorder-7 score ranges from 0-21, out of which 0-4 means minimal anxiety, 5-9 stands for mild anxiety, 10-14 for moderate and 15-21 for severe anxiety.	Change in score before the intervention on 1st day of intervention and on 3rd day one hour after the intervention.