Clinical Trial Details
— Status: Completed
Administrative data
| NCT number |
NCT04646616 |
| Other study ID # |
3R21MD012352-02S1 |
| Secondary ID |
|
| Status |
Completed |
| Phase |
N/A
|
| First received |
|
| Last updated |
|
| Start date |
January 15, 2021 |
| Est. completion date |
March 4, 2022 |
Study information
| Verified date |
June 2023 |
| Source |
Drexel University |
| Contact |
n/a |
| Is FDA regulated |
No |
| Health authority |
|
| Study type |
Interventional
|
Clinical Trial Summary
Latinos have been one of the racial/ethnic groups most impacted by the COVID-19 pandemic, and
evidence of effective strategies to curb the pandemic, reduce disparities, and mitigate its
impact is lacking and very urgent.
The goal of this competitive revision is to expand an ongoing academic-community partnership
to adapt, implement, and evaluate a multi-level intervention to mitigate the
multi-dimensional toll of COVID19 among Latino immigrant communities in Philadelphia.
Description:
This goal of this competitive revision is to expand our original project to adapt, implement
and evaluate a multi-level intervention to mitigate the multi-dimensional toll of COVID19
among Latino immigrant communities in Philadelphia. Evidence of effective strategies to curb
the pandemic, reduce disparities and mitigate its impact is lacking and very urgent. In the
US, Latino immigrants are one of the groups hardest hit by this pandemic, with recent steep
increases in COVID-19 deaths among this group corroborating their continued increased risk of
infection and increased susceptibility. Latino immigrants have long exhibited disparities in
diabetes, obesity and hypertension, factors known to increase COVID-19 related severity, and
also in Substance Abuse, Violence exposure, HIV/AIDS, and MEntal health (SAVAME) syndemic.
These syndemic conditions have been worsened in the context of COVID-19. Latino immigrants
represent a hard-to-reach and marginalized population, with extremely limited access to
adequate health care and safety nets. This group faces many structural barriers, and social
vulnerabilities, that hinder their capacity to access COVID-19 testing and treatment services
and to adhere to public health interventions and measures to decrease the spread of COVID-19.
Latinos often rely on a thin and fragmented network of health and social services
organizations. Intervention to mitigate the impact of COVID-19 on this population will need
to have a broad stakeholder engagement and address a wide range of health determinants.
Peer-driven interventions have been effective for the prevention and control of infectious
diseases such as HIV, STIs among Latino populations. Strengthening the links between
community members and these organizations and promoting inter-organizational coordination to
meet syndemic health, behavioral, economic, and legal needs of Latino communities are
essential elements to mitigate the impact of COVID-19 on this low-resource population. In
direct response to the NOT-MD-20-022/PAR PA-18-935, our ongoing community-academic
partnership proposes to evaluate "CRISOL Contigo," a multi-level intervention to address the
needs created or magnified by the COVID-19 pandemic among Latino communities in Philadelphia.
CRISOL Contigo includes a peer-driven program and mobilization of Latino-serving
organizations. In aim 1, the investigative team will adapt an ongoing Popular Opinion Leader
(POL) program to address the unique health, social, and economic needs related to COVID-19
and the SAVAME syndemic. In aim 2, the investigative team will assess the efficacy of CRISOL
Contigo to improve COVID-19 related preventive health behaviors and use and access to
COVID-19 related testing and care (co-primary outcomes). In aim 3, the investigative team
will examine the impact of CRISOL Contigo on community assets, interagency collaborations,
and coordination among the Latino-serving organizations in Philadelphia. There are almost 20
million Latino immigrants in the US, and they play a central role in sustaining the vital
parts of the US economy Tailored, multi-level interventions that consider the unique needs of
Latinos are urgently needed to mitigate the impact of this and future outbreaks of COVID-19
on this disadvantaged population.
