COVID-19 Clinical Trial
Official title:
Methylene Blue-mediated Photodisinfection for SARS-CoV-2 in the Upper Respiratory Tract
Verified date | October 2021 |
Source | Sunnybrook Health Sciences Centre |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The study proposes to test photodisinfection (PDF) on SARS-CoV-2 in the nose. The study will use Health Canada approved Steriwave™ Nasal Decolonization (ND) in he nostril of patients infected with SARS-CoV-2. Participants are swabbed for SARS-CoV-2 before and after the PDF treatment. For the study, a small group of healthcare workers who have tested positive for SARS-CoV-2 will be included. They will not undergo the treatment but will need to swab their noses multiple times over the next 5 days. This nil group will provide the effect (if any) of swabbing SARS-CoV-2 levels in the nose.
Status | Completed |
Enrollment | 45 |
Est. completion date | October 19, 2021 |
Est. primary completion date | July 7, 2021 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A and older |
Eligibility | Inclusion Criteria (patient population): - Recent SARS-CoV-2+ diagnosis - Present in hospital Inclusion Criteria (healthcare workers): - Recent SARS-CoV-2+ diagnosis - Ability to self-administer nasal swabs Exclusion Criteria (patient population): - Immediate requirement for intubation (i.e. emergency airway) or inability to maintain independent oral airway Exclusion Criteria (healthcare workers): - None |
Country | Name | City | State |
---|---|---|---|
Canada | Sunnybrook Health Sciences Centre | Toronto | Ontario |
Lead Sponsor | Collaborator |
---|---|
Sunnybrook Health Sciences Centre |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | RT-qPCR | The main endpoint is microbiological; RT-qPCR will be conducted on the pre and post treatment swabs and the change in cycle threshold value will be measured | 30 minutes |
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