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Clinical Trial Summary

Purpose: - To determine the presence of SARS-CoV-2 in tears - To determine SARS-CoV-2 receptors in tear production system


Clinical Trial Description

This is a prospective case series. NP swab and tear samples will be collected simultaneously from the confirmed or suspected COVID-19 patients. The samples will be transferred to the lab for SARS-CoV-2 testing. The presence of absence of SARS-CoV-2 will be compared in tears versus NP swabs. The second part of the study is a histopathology examination series. Normal lacrimal gland and ocular surface tissue samples already stored at the UMN ocular pathology lab and Lion's Gift of Sight Eye Bank will be used for IHC staining for ACE2 and similar targets. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04526769
Study type Observational
Source University of Minnesota
Contact
Status Completed
Phase
Start date September 1, 2021
Completion date December 30, 2021

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