COVID-19 Critically Ill Patients' Evolution After Medical Transport by Train From Paris Intensive Care Units to West of France Intensive Care Units

COVID-19 Clinical Trial

— TOCCIP  

Official title:

COVID-19 Critically Ill Patients' Evolution After Medical Transport by Train From Paris Intensive Care Units to West of France Intensive Care Units

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04433325
• Other study ID #: 35RC20_3091_TOCCIP
• Status: Not yet recruiting
• Start date: June 2020
• Est. completion date: September 2020

Study information

• Verified date: June 2020
• Source: Rennes University Hospital
• Contact: Nicolas Mevel
• Phone: 0299282555
• Email: dri[@]chu-rennes.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Since early 2020, France knows a sanitary crisis with a massive influx of COVID-19 patients admitted in Intensive Care Units (ICU). It led to a saturation of the French health system, especially in some geographic areas such as East of France or Paris region. Therefore, authorities decided to transfer some critically ill patients from these crowded ICUs to less busy regional ICUs. it was done for the first time by medical train transportation. Knowing that the investigators lack experience regarding this type of medical evacuation, regarding the high number of transferred patients, with such a logistic effort, the investigators decided to study this phase of the COVID-19 sanitary crisis in order to draw a feedback. So far, there are no data in the literature regarding this topic.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 150
• Est. completion date: September 2020
• Est. primary completion date: July 2020
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Age > 18 years

• COVID-19 positive patients admitted in Intensive Care Unit between 15/03/2020 and 15/04/2020

• Patients (or legal representative) with no opposition to inclusion in medical research protocol

• Regarding case group : Patients transferred from Paris's ICU

• Regarding case control group : Patients admitted in ICU with no transfer from Paris

Exclusion Criteria:

• > 18 years under legal protection and patients with liberty restriction

Related Conditions & MeSH terms

• COVID-19
• Critical Illness
• Intensive Care Unit Syndrome

Locations

Country	Name	City	State
France	CHU Poitiers	Poitiers
France	CHU Tours	Tours

Sponsors (1)

Lead Sponsor	Collaborator
Rennes University Hospital

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	number of death	to evaluate mortality	at Intensive Care Units discharge, an average of 1 months
Secondary	number of infections	to evaluate morbidity	from date of admission until Intensive Care Units discharge, assessed up to 1 months
Secondary	number of days of mechanical ventilation		from date of admission until Intensive Care Units discharge, assessed up to 1 months
Secondary	number of days of sedation		from date of admission until Intensive Care Units discharge, assessed up to 1 months
Secondary	number of days of use of neuromuscular blocking agents		from date of admission until Intensive Care Units discharge, assessed up to 1 months
Secondary	number of days of vasopressor use		from date of admission until Intensive Care Units discharge, assessed up to 1 months
Secondary	number of days in Intensive Care Units		from date of admission until Intensive Care Units discharge, assessed up to 1 months
Secondary	number of days in hospital		from date of admission until hospital discharge, assessed up to 1 months