COVID-19 Clinical Trial
Official title:
Emergency Laparotomies and Outcomes During the COVID-19 Pandemic - a Retrospective Cohort Study
NLR has previously been observed to correlate with complications in upper GI (1) and
colorectal (2) surgery. The investigators sought to assess if a similar correlation can be
identified in emergency general surgical patients and if the presence of suspected or
confirmed COVID-19 may impact on this.
Given the heterogeneity of emergency general surgery the investigators therefore plan to
perform a retrospective review of patients having emergency laparotomies only at a single NHS
site during COVID-19 pandemic. Assessment of outcomes and Neutrophil:lymphocyte ratio as a
predictor of outcomes will be completed. Outcomes will be completed in line with the recent
COVIDSurg study criteria (3). The primary outcome is 30-day mortality. Secondary outcomes are
7-day mortality, re-operation, length of stay, post-operative respiratory failure,
post-operative ARDS (Acute Respiratory Distress Syndrome), post-operative sepsis and ITU
(Intensive Therapy Unit)/HDU (High Dependency Unit) admission.
n/a
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