COVID-19 Clinical Trial
Official title:
Evaluating Effectiveness of Barrier Measures to Limit Nosocomial Transmission: Covid-19 Prevalence Survey Among Caregivers With Various Exposures
Use lay language. The Covid-19 pandemic hit France in March 2020 and stage 3 of the epidemic
justified the introduction of national and unprecedented containment measures from March 17,
2020. The Montpellier CHU experienced peak hospitalizations of Covid-19 infections in late
March. The estimate of the proportion of infected people in Occitania, South of France, for
the 11th of May 2020 is 3.1% (95% CI: 1.9-5.9) for the Occitania region, to which Montpellier
belongs.
In the context of the Covid-19 epidemic, notably due to the absence of pharmacological or
vaccine prophylaxis, barrier measures were of crucial importance, especially for exposed
caregivers. These measures include an adaptation of individual behavior, the creation of a
so-called "Covid" hospital, the wearing of specific equipment in all departments, the use in
the rooms of Covid-19 patients of a gown, an apron, gloves, and a FFP2 type mask in the event
of contact and sampling, protocolized and standardized bio-cleaning measures, a
reorganization of the premises and the definition of specific circuits.
In view of the second wave of the epidemic, estimating the effectiveness of the barrier
measures is of major importance. The investigators therefore propose an evaluation of the
effectiveness of these measures, by comparing the serological prevalence of infection among
caregivers working directly in COVID units compared to caregivers working in services
excluding the management of Covid-19 patients.
Systematic evaluation in COVID-19 units of Sarc-Co-V2 infection will also be assessed, with
naso-pharyngeal swabs.
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